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Gene Ontology Information

Protein Name Ade13p
Description Adenylosuccinate lyase; catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency; human ADSL can complement yeast ADE13 null mutant
GO Terms:
Biological Process		 level 7: purine nucleotide biosynthetic process external link
level 8: purine ribonucleotide biosynthetic process external link
level 10: 'de novo' IMP biosynthetic process external link
level 10: 'de novo' AMP biosynthetic process external link
GO Terms:
Molecular Function		 level 2: catalytic activity external link
level 3: lyase activity external link
level 6: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity external link
level 6: N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity external link
GO Terms:
Cellular Component		 level 1: cellular_component external link
level 3: cytosol external link
External source Open in SGD external link
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