S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sec61p
Description	Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex is required for SRP-independent protein translocation into the ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER
GO Terms: Biological Process	level 5: protein transmembrane import into intracellular organelle level 5: protein transport level 6: retrograde protein transport, ER to cytosol level 6: post-translational protein targeting to membrane, translocation level 6: amide transport level 6: SRP-dependent cotranslational protein targeting to membrane, translocation level 6: misfolded protein transport level 7: ubiquitin-dependent ERAD pathway
GO Terms: Molecular Function	level 4: protein transmembrane transporter activity level 4: protein-transporting ATPase activity level 5: ribosome binding level 5: peptide transmembrane transporter activity level 5: signal sequence binding
GO Terms: Cellular Component	level 3: membrane level 4: endoplasmic reticulum level 4: integral component of membrane level 5: Sec61 translocon complex level 5: endoplasmic reticulum membrane
External source	Open in SGD