S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ubx2p
Description	Bridging factor involved in ER-associated protein degradation (ERAD); bridges the cytosolic Cdc48p-Npl1p-Ufd1p ATPase complex and the membrane associated Ssm4p and Hrd1p ubiquitin ligase complexes; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain; redistributes from the ER to lipid droplets during the diauxic shift and stationary phase; required for the maintenance of lipid homeostasis; required for mitochondrial protein translocation-associated degradation
GO Terms: Biological Process	level 6: lipid droplet organization level 7: mitochondrial protein processing level 7: proteasome-mediated ubiquitin-dependent protein catabolic process level 7: ubiquitin-dependent ERAD pathway level 8: mitochondria-associated ubiquitin-dependent protein catabolic process
GO Terms: Molecular Function	level 3: protein-macromolecule adaptor activity level 3: protein-containing complex binding level 5: ubiquitin binding
GO Terms: Cellular Component	level 3: membrane level 4: endoplasmic reticulum level 4: integral component of membrane level 5: Doa10p ubiquitin ligase complex level 5: endoplasmic reticulum membrane level 5: lipid droplet level 5: integral component of plasma membrane level 6: Hrd1p ubiquitin ligase ERAD-L complex level 6: mitochondrial outer membrane level 6: integral component of endoplasmic reticulum membrane
External source	Open in SGD