S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tsa1p
Description	Thioredoxin peroxidase; acts as both ribosome-associated and free cytoplasmic antioxidant; self-associates to form a HMW chaperone complex under oxidative stress; chaperone activity essential for growth in zinc deficiency; hydrogen peroxide receptor and signal transducer in a light sensing pathway; required for telomere length maintenance; binds and modulates Cdc19p activity; protein abundance increases and forms cytoplasmic foci during DNA replication stress
GO Terms: Biological Process	level 3: protein folding level 4: cell redox homeostasis level 4: regulation of catalytic activity level 4: chaperone-mediated protein folding level 4: cellular oxidant detoxification level 5: DNA protection level 5: response to hydroperoxide level 5: cellular response to oxidative stress level 6: DNA damage checkpoint signaling level 7: regulation of gluconeogenesis
GO Terms: Molecular Function	level 2: antioxidant activity level 3: oxidoreductase activity level 3: peroxidase activity level 4: unfolded protein binding level 4: peroxiredoxin activity level 4: kinase regulator activity level 5: ribosome binding level 5: thioredoxin-dependent peroxiredoxin activity level 6: thioredoxin peroxidase activity
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 4: polysome
External source	Open in SGD