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Gene Ontology Information

Protein Name Mdm1p
Description PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs; anchored in the ER membrane at nucleus-vacuole junctions and binds phosphatidylinositol 3-phosphate (PtdIns-3-P) in the vacuolar membrane via its Phox homology (PX) domain; expressed predominantly in late G1 to early S phase of the cell cycle; mutation affects nuclear and mitochondrial transmission to daughter buds; similar to 4 human genes, one of which (SNX14) is associated with neurological disease
GO Terms:
Biological Process		 level 5: vacuole-ER tethering external link
level 6: mitochondrion inheritance external link
GO Terms:
Molecular Function		 level 5: phosphatidylinositol binding external link
level 7: phosphatidylinositol-3-phosphate binding external link
GO Terms:
Cellular Component		 level 3: cell periphery external link
level 3: cytoplasm external link
level 4: intracellular membrane-bounded organelle external link
level 4: nucleus-vacuole junction external link
level 6: fungal-type vacuole external link
External source Open in SGD external link
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