S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ccs1p
Description	Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within N-terminus is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress; human homolog CCS can complement yeast ccs1 null mutant
GO Terms: Biological Process	level 5: superoxide metabolic process level 5: removal of superoxide radicals level 6: protein maturation by copper ion transfer
GO Terms: Molecular Function	level 3: superoxide dismutase activity level 5: superoxide dismutase copper chaperone activity level 5: metal ion binding level 7: copper ion binding
GO Terms: Cellular Component	level 3: cytosol level 3: cytoplasm level 4: mitochondrion level 5: nucleus level 6: mitochondrial intermembrane space level 6: mitochondrial inner membrane
External source	Open in SGD