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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Sla2p
Description
Adaptor protein that links actin to clathrin and endocytosis; involved in membrane cytoskeleton assembly and cell polarization; present in the actin cortical patch of the emerging bud tip; dimer in vivo
GO Terms:
Biological Process
level 5:
actin filament organization
level 6:
endocytosis
level 6:
actin cortical patch assembly
level 7:
clathrin coat assembly
level 9:
negative regulation of Arp2/3 complex-mediated actin nucleation
GO Terms:
Molecular Function
level 1:
molecular_function
level 4:
actin filament binding
level 4:
phospholipid binding
level 4:
clathrin binding
level 5:
phosphatidylinositol-3,4-bisphosphate binding
level 5:
actin binding
level 5:
phosphatidylinositol-3,5-bisphosphate binding
level 5:
clathrin light chain binding
level 5:
clathrin adaptor activity
GO Terms:
Cellular Component
level 3:
membrane
level 3:
cytoplasm
level 4:
incipient cellular bud site
level 4:
mating projection tip
level 4:
integral component of membrane
level 4:
actin cortical patch
level 4:
plasma membrane
level 4:
cellular bud tip
level 4:
cellular bud neck
level 4:
cell cortex
level 5:
cytoskeleton
level 6:
clathrin-coated vesicle
External source
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