S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tof1p
Description	Subunit of a replication-pausing checkpoint complex; Tof1p-Mrc1p-Csm3p acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase; relocalizes to the cytosol in response to hypoxia
GO Terms: Biological Process	level 3: meiotic cell cycle level 3: cell cycle level 5: cellular response to DNA damage stimulus level 5: mitotic sister chromatid cohesion level 6: maintenance of DNA repeat elements level 6: DNA replication level 6: DNA repair level 7: DNA replication checkpoint signaling level 7: replication fork arrest level 7: replication fork protection level 8: negative regulation of DNA replication
GO Terms: Molecular Function	level 1: molecular_function level 5: DNA binding
GO Terms: Cellular Component	level 3: cytosol level 4: replication fork protection complex level 4: nuclear replication fork level 5: nucleus
External source	Open in SGD