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Gene Ontology Information

Protein Name Sec12p
Description Guanine nucleotide exchange factor (GEF); activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER; SEC12 has a paralog, SED4, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 4: regulation of catalytic activity external link
level 5: vesicle-mediated transport external link
level 5: protein secretion external link
level 5: protein transport external link
level 7: regulation of COPII vesicle coating external link
GO Terms:
Molecular Function		 level 5: GTPase activator activity external link
level 6: guanyl-nucleotide exchange factor activity external link
GO Terms:
Cellular Component		 level 3: membrane external link
level 4: integral component of membrane external link
level 4: endoplasmic reticulum external link
level 4: Golgi apparatus external link
level 5: endoplasmic reticulum membrane external link
level 6: integral component of endoplasmic reticulum membrane external link
External source Open in SGD external link
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