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Gene Ontology Information

Protein Name Apm4p
Description Cargo-binding mu subunit of AP-2; AP-2 is a heterotetrameric endocytic cargo-binding adaptor that facilitates uptake of membrane proteins during clathrin-mediated endocytosis; Apm4p is required for AP-2 function and localization, and binds cell wall stress receptor Mid2p; AP-2 is required for cell polarity responses to pheromone, nutritional status and cell wall damage in S. cerevisiae, and for hyphal growth in C. albicans; AP-2 complex is conserved in mammals
GO Terms:
Biological Process
level 5: vesicle-mediated transport external link
level 5: intracellular protein transport external link
level 5: protein transport external link
level 6: endocytosis external link
level 8: clathrin-dependent endocytosis external link
GO Terms:
Molecular Function
level 3: protein binding external link
level 5: clathrin adaptor activity external link
GO Terms:
Cellular Component
level 3: membrane external link
level 3: cytosol external link
level 4: cytoplasmic vesicle external link
level 4: clathrin-coated pit external link
level 5: AP-2 adaptor complex external link
level 5: clathrin adaptor complex external link
level 7: clathrin-coated vesicle membrane external link
External source Open in SGD external link
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