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Gene Ontology Information

Protein Name Trm10p
Description tRNA methyltransferase; methylates the N-1 position of guanine at position 9 in tRNAs; protein abundance increases in response to DNA replication stress; member of the SPOUT (SpoU-TrmD) methyltransferase family; human ortholog TRMT10A plays a role in the pathogenesis of microcephaly and early onset diabetes; an 18-mer originates from the TRM10 locus; genetic analysis shows the 18-mer is the translation regulator
GO Terms:
Biological Process		 level 3: methylation external link
level 6: tRNA methylation external link
level 7: tRNA N1-guanine methylation external link
level 8: tRNA processing external link
GO Terms:
Molecular Function		 level 3: transferase activity external link
level 5: methyltransferase activity external link
level 6: tRNA binding external link
level 7: tRNA (guanine) methyltransferase activity external link
level 8: tRNA (guanine-N1-)-methyltransferase activity external link
level 9: tRNA (guanine(9)-N(1))-methyltransferase activity external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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