S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Vps21p
Description	Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication
GO Terms: Biological Process	level 5: protein transport level 5: intracellular protein transport level 6: protein targeting to vacuole level 6: Golgi to endosome transport level 6: endocytosis level 7: late endosome to vacuole transport via multivesicular body sorting pathway level 7: protein localization to endosome level 7: multivesicular body assembly level 7: reticulophagy level 7: vacuole inheritance
GO Terms: Molecular Function	level 4: nucleotide binding level 6: GTP binding level 8: GTPase activity
GO Terms: Cellular Component	level 3: membrane level 3: cytosol level 4: mitochondrion level 4: endosome level 5: mitochondrial membrane level 5: early endosome level 5: late endosome level 5: endosome membrane level 6: mitochondrial outer membrane
External source	Open in SGD