S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Wtm2p
Description	Transcriptional modulator; involved in regulation of meiosis, silencing, and expression of RNR genes; involved in response to replication stress; contains WD repeats; relocalizes to the cytosol in response to hypoxia; WTM2 has a paralog, UME1, that arose from the whole genome duplication
GO Terms: Biological Process	level 3: meiotic cell cycle level 3: protein-containing complex localization level 4: negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle level 5: cellular response to DNA damage stimulus level 6: chromatin remodeling level 7: regulation of DNA-templated transcription level 7: histone deacetylation level 9: negative regulation of silent mating-type cassette heterochromatin formation level 9: positive regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 3: protein binding level 4: DNA-binding transcription factor activity, RNA polymerase II-specific level 4: transcription corepressor activity level 4: histone binding
GO Terms: Cellular Component	level 3: cytosol level 3: cytoplasm level 4: Rpd3L-Expanded complex level 5: Rpd3L complex level 5: nucleus
External source	Open in SGD