S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Clp1p
Description	Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation and in gene looping which affects reinitiation of transcription; mutations in human ortholog cause cerebellar neurodegeneration
GO Terms: Biological Process	level 6: RNA processing level 7: mRNA processing level 8: mRNA polyadenylation level 8: mRNA 3'-end processing level 9: tRNA splicing, via endonucleolytic cleavage and ligation level 9: pre-mRNA cleavage required for polyadenylation
GO Terms: Molecular Function	level 4: nucleotide binding level 5: RNA binding level 6: polynucleotide 5'-hydroxyl-kinase activity level 6: ATP binding
GO Terms: Cellular Component	level 4: mRNA cleavage factor complex level 5: nucleus
External source	Open in SGD