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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Bro1p
Description
Cytoplasmic class E vacuolar protein sorting (VPS) factor; coordinates protein sorting and deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes
GO Terms:
Biological Process
level 4:
response to nutrient
level 5:
vacuolar transport
level 5:
protein transport
level 6:
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
level 6:
multivesicular body sorting pathway
level 7:
protein deubiquitination
level 7:
late endosome to vacuole transport via multivesicular body sorting pathway
level 7:
protein localization to endosome
level 7:
intralumenal vesicle formation
level 8:
ubiquitin-dependent protein catabolic process
level 8:
mitochondria-associated ubiquitin-dependent protein catabolic process
level 8:
ATP export
level 8:
positive regulation of ubiquitin-specific protease activity
GO Terms:
Molecular Function
level 3:
protein binding
level 6:
deubiquitinase activator activity
GO Terms:
Cellular Component
level 3:
cytoplasm
level 3:
cytosol
level 4:
endosome
level 5:
endosome membrane
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