S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Vps30p
Description	Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy, Complex II is required for vacuolar protein sorting; required for overflow degradation of misfolded proteins when ERAD is saturated; C-terminus has novel globular fold essential for autophagy through the targeting of the PI3-kinase complex I to the pre-autophagosomal structure; ortholog of higher eukaryote gene Beclin 1; human BECN1 can complement yeast null mutant
GO Terms: Biological Process	level 4: cytoplasm to vacuole transport by the Cvt pathway level 4: autophagy level 5: protein transport level 5: macroautophagy level 5: autophagy of peroxisome level 6: late endosome to vacuole transport level 6: cellular response to nitrogen starvation level 6: piecemeal microautophagy of the nucleus level 6: retrograde transport, endosome to Golgi level 7: phosphatidylinositol biosynthetic process level 7: autophagosome assembly
GO Terms: Molecular Function	level 1: molecular_function
GO Terms: Cellular Component	level 3: membrane level 3: cytoplasm level 3: extrinsic component of membrane level 3: cytosol level 3: phagophore assembly site level 4: vacuole-isolation membrane contact site level 4: endosome level 4: vacuole level 4: phagophore assembly site membrane level 5: vacuolar membrane level 5: endosome membrane level 6: phosphatidylinositol 3-kinase complex, class III, type I level 6: phosphatidylinositol 3-kinase complex, class III, type II level 7: fungal-type vacuole membrane
External source	Open in SGD