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Gene Ontology Information

Protein Name Tbf1p
Description Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation
GO Terms:
Biological Process
level 3: cell cycle external link
level 6: chromatin remodeling external link
level 7: telomere maintenance via telomere lengthening external link
level 8: regulation of transcription by RNA polymerase II external link
level 9: negative regulation of telomere maintenance via telomerase external link
level 9: snoRNA transcription by RNA polymerase II external link
GO Terms:
Molecular Function
level 4: DNA-binding transcription factor activity, RNA polymerase II-specific external link
level 5: protein homodimerization activity external link
level 5: DNA binding external link
level 5: chromatin insulator sequence binding external link
level 7: telomeric DNA binding external link
level 7: double-stranded telomeric DNA binding external link
level 8: RNA polymerase II cis-regulatory region sequence-specific DNA binding external link
GO Terms:
Cellular Component
level 4: chromosome, telomeric region external link
level 5: chromosome external link
level 5: nucleus external link
External source Open in SGD external link
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