S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	YPL191C
Description	K48-specific deubiquitinating (DUB) enzyme; MINDY family endo-type deubiquitinase that preferentially cleaves long K48-linked polyubiquitin chains between moieties; diploid deletion strain exhibits high budding index; GFP-fusion protein localizes to the cytoplasm endoplasmic reticulum and cell periphery in high-throughput studies; YPL191C has a paralog, YGL082W, that arose from the whole genome duplication; ortholog of human MINDY2/FAM63B
GO Terms: Biological Process	level 5: proteolysis level 8: protein K48-linked deubiquitination
GO Terms: Molecular Function	level 3: hydrolase activity level 4: peptidase activity level 5: cysteine-type peptidase activity level 6: cysteine-type deubiquitinase activity level 7: cysteine-type carboxypeptidase activity level 7: Lys48-specific deubiquitinase activity
GO Terms: Cellular Component	level 3: cytoplasm level 3: cell periphery level 4: endoplasmic reticulum
External source	Open in SGD