Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Hrr25p Description
Conserved casein kinase, monopolin subunit; regulates diverse events including vesicular traffic, DNA repair, CVT pathway, cohesion cleavage, attachment of sister kinetochores at meiosis I, exit from meiosis II, and ribosomal subunit biogenesis; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p; homolog of mammalian CK1delta
GO Terms:
level 3: signal transduction autophagy of peroxisome cellular response to DNA damage stimulus monopolar spindle attachment to meiosis I kinetochore DNA repair protein phosphorylation regulation of protein localization endocytosis ribosomal large subunit biogenesis ribosomal small subunit biogenesis phosphorylation regulation of ER to Golgi vesicle-mediated transport peptidyl-serine phosphorylation peptidyl-tyrosine phosphorylation regulation of autophagosome assembly regulation of vesicle fusion with Golgi apparatus positive regulation of clathrin-dependent endocytosis regulation of protein localization by the Cvt pathway tRNA wobble uridine modification GO Terms:
level 3: transferase activity nucleotide binding protein kinase activity protein tyrosine kinase activity kinase activity protein serine/threonine kinase activity ATP binding GO Terms:
level 3: nucleoplasm phagophore assembly site monopolin complex cytoplasm cytosol plasma membrane cellular bud tip cellular bud neck chromosome, centromeric region Golgi apparatus spindle pole body nucleus preribosome, small subunit precursor nucleolus peroxisome P-body External source
Open in SGD
