S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Cet1p
Description	RNA 5'-triphosphatase involved in mRNA 5' capping; subunit of mRNA capping enzyme, which is a heterotetramer composed of a Cet1p homodimer and two molecules of guanylyltransferase Ceg1p; Cet1p also has a role in regulation of RNAPII pausing at promoter-proximal sites; interaction between Cet1p and Ceg1p is required for Ceg1p nuclear import; mammalian enzyme is single bifunctional polypeptide; human homolog RNGTT can complement yeast cet1 null mutant
GO Terms: Biological Process	level 7: mRNA processing level 7: polynucleotide 5' dephosphorylation level 7: positive regulation of protein localization to nucleus level 8: 7-methylguanosine mRNA capping level 10: positive regulation of transcription elongation by RNA polymerase II
GO Terms: Molecular Function	level 3: hydrolase activity level 7: polynucleotide 5'-phosphatase activity
GO Terms: Cellular Component	level 4: mRNA cap methyltransferase complex level 5: nucleus
External source	Open in SGD