S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Hsp82p
Description	Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; promotes solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication; human homolog, HSP90AB1, complements null mutant
GO Terms: Biological Process	level 3: protein folding level 4: 'de novo' protein folding level 4: response to osmotic stress level 4: protein refolding level 5: protein stabilization level 5: protein maturation level 5: cellular response to heat level 6: protein targeting to mitochondrion level 7: proteasome assembly level 8: box C/D snoRNP assembly level 9: positive regulation of telomere maintenance via telomerase
GO Terms: Molecular Function	level 3: ATP-dependent protein folding chaperone level 3: ATP hydrolysis activity level 4: unfolded protein binding level 4: nucleotide binding level 6: ATP binding
GO Terms: Cellular Component	level 2: protein-containing complex level 3: perinuclear region of cytoplasm level 3: cytoplasm level 3: cytosol level 4: plasma membrane level 5: nucleus
External source	Open in SGD