S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Tif5p
Description	Translation initiation factor eIF5; functions as both a GTPase-activating protein (GAP) that stimulates the hydrolysis of GTP bound to eIF-2, as part of the 43S preinitiation complex, and as a GDP dissociation inhibitor (GDI) to prevent recycling of eIF2; human ortholog eIF5 complements the yeast null mutant
GO Terms: Biological Process	level 4: regulation of catalytic activity level 4: translational initiation level 5: translation level 6: formation of translation preinitiation complex level 6: formation of cytoplasmic translation initiation complex level 8: mature ribosome assembly level 8: regulation of translational initiation level 9: negative regulation of translational initiation
GO Terms: Molecular Function	level 3: protein binding level 4: nucleotide binding level 4: translation initiation factor binding level 5: translation initiation factor activity level 5: GTPase activator activity level 5: eukaryotic initiation factor eIF2 binding level 6: GDP-dissociation inhibitor activity level 6: GTP binding level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cytosol level 4: multi-eIF complex level 5: eukaryotic 48S preinitiation complex
External source	Open in SGD