S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rox1p
Description	Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance
GO Terms: Biological Process	level 5: cellular response to osmotic stress level 8: regulation of transcription by RNA polymerase II level 9: negative regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 4: DNA-binding transcription factor activity, RNA polymerase II-specific level 4: transcription corepressor activity level 5: DNA-binding transcription repressor activity, RNA polymerase II-specific level 5: DNA binding level 6: DNA binding, bending level 6: sequence-specific DNA binding level 7: cis-regulatory region sequence-specific DNA binding level 8: RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO Terms: Cellular Component	level 3: chromatin level 5: nucleus
External source	Open in SGD