Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ALK2
Systematic Name
YBL009W
Strain
S288c
Description
Atypical protein kinase; along with its paralog, ALK1, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; negatively regulates the morphogenesis checkpoint in response to polarity insults in opposition to ALK1; phosphorylated in response to DNA damage; similar to mammalian haspins
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ALK2 YBL009W
ATGAATTTTGATGCGGTAGCAGATCAACAGATGACTGACAGAAGGTATTTTGCTCTCGAA
GTAGCAGAAAGCGATGATGCCGACAGCTCATTAAATTCTTCATCCATGGGAAGCCCCGCA
GTGGATGTAGGAAGAAAAGTTTACAAAATCACTTCGCACAAGGGTTCAGCAGAAGATGAG
AGTCAATCCTTTTTTACTTCTTCAGATTCTCCAACATCCAAAACAAGGCCTGTAGGTAAA
ACCATCGAAAACGATGATTACTATGGTAAAAGATCTTCTACAGGTTCATCGCTCAAACAA
CTCTTCAATAAAATTAATATTAATGATACCGCTCACTCTTCAAACAAAGAAAATGTATCT
CAGTCGGTGCTATCGGAAAACAAGCTGCTCTCTCCATCTAAAAGGTTGTCGAAGCAAGGT
CTTACAAAGGTGACTAACTCCAAGTTTCGTACACCCTTGAGACCTATTTCAAACCAATCG
ACTTTATCAAGGGATGAGCCTGTTAAAGATTTTAGATCACTTAAGTTTCGGAGCGGTAGT
GATTTCAAATGCTGGGGTGACGAGAAGACAAGTTCTCATGTTCATTCATCCAGTGTGAAC
TCAGTTAATTCCTTTACTTCTACCACCTCTTCTTCAAAGTGGAAGTTCTGGAAAAATGAT
AACCTATTGTCGAGGTCGCTATCTTCCAGATCTGTGAATGACCAAGATCCGAACTTTGTT
CAGCCAAAACCAACCAATTCGTTACAAAAGAAGTCTTCAATTTCAAGTTTTCACAATTCT
ATTTTTGGTGGTGGCAAACACACAGAGAAGAAGAGGAATTCTGGATTTATTATGCCCGAT
CATCAGAGCACGAAGGAGCTAAACCACAAACATTCATCATCGAACCTTTCCTTTAGAAGT
TTGAAGCATAAAACATCACATTCTTCACTAAATAAGCTCAAAGTAAGGCGTAAAGGAAAT
ACACAAGAACTGAATCATCCGATCAAAAAAACTTGCCAAATATCATTGCCTGTTCCAGAC
CAAGTCTCAAAGGACAAGATTCAACTGAAATTGAAAAATTCAACATCATTGGCATCCTTA
TCTTCAGAAGTCACTCCCATAAACACTTTGGACTACAATGATTCAATTTTGCAACAAATA
TTACAACTTTGTGATGTTAAGTATATATTACATGATCTACGTGAAGCTCAGTCATTAGGC
TTGTTTACGTTGAATACTAGATCGGTTCAGCTGTCTCATAACTTTTGGCAAACTTATCAT
AGCGATATGCAAACTTCACTCATTTGCAAGAAAGTATGTCTAGGGGCTCTAAGTGATTTG
ACTACTTCAAACTTGATATCCTTACATGAATTGAAATCATTACGGTTAATACAAGGAACT
AGCGGTGTCGCCAATTTACTGCAAGCTTATGTTGTGCCCTCAAATCAATGTGAAAATGAC
CAAAACTTGATACTGTACTTATTTTTCAAATACCAGGGAACTCCTCTATCAAGGTGCTCT
AACATTGATTACTCTCAAGCATTGTCTATTTTCTGGCAGTGCAGCAGTATTTTATATGTT
GCTGAATCCAAATTTCAGCTCGAACACAGGAATCTAACTTTGGACCATATTTTGATAGAC
TCTAAAGGGAATGTTACTTTAATTGATATGAAGTGCTGTCGTTTCTTGAATATAGACAAC
AATAAGGCTTCCTATACAAGATTAGACCATCATTATTTCTTCCAAGGCCGGGGGACTCTT
CAATTCGAGATATATGAACTGATGAGAAGCATGCTGCCTCAGCCAATATCCTGGGCTACA
TTTGAACCAAGAACAAACCTATTATGGTTATATCACCTAAGTAGCAGCCTGCTAAAAATG
GCCAAAAAAGCCGTAGTCAGCGGCGCTTTGAACCGGGAAGAAAATATCTTAATCGAGTTG
ACGCACTTACTCGATCCTGCTCGAAAACATTCCAAAACAATTTTCAAAAAGGAACTTGTT
ATAAGAACTTGCGGTGATTTGTTATCTTTGAAGGGAGAAATAATGCAGTAA
Promoter Sequence
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>ALK2 YBL009W
TCCTGTCAAATTCGTCACTACATTTTCAAAAGTTGTCTTATCCTTTAGGAGGTCTCGCTG
TTGTTTCTTCAATGATCTTGATTTACTAACCAAAAAGTCAATGGATTGACACAATGTATC
GTGGTATTGGCGTAAAGATTCTTCATCCATACTAGTAAAATCTGCCATAAGCAATTGCGG
TATATGCTGCTCTTGCTCACGCTCCTCTTCCTTTTGAAGAGATTTTAAAGTCATTGGTGG
TGTATAGTCAATTTTGAAATTATCCCTCAGGAAGAGACCAGTAGCCGTTTGCTCATTTTT
CTCCACTGCATCGCATATCCTTTTGAACAACTCATCATTCAACGGTTCTTCCTCCCTCTT
CGTACCAACACCCTCAGAGCCATTATTATCCGATAATCTCAAAATGTGGAGCAAGTTTCT
GCGTATATGAGATTTATTCCATATGAATGGCTGTAACACAGGATCTAATTGTACGAGTTG
TTCATAAATGACATGGGGTCGTTCATCTTCAATAAGTTTGCTCAGCTTGAAACAGTCATT
CTTTATGGTTTCTTCTTCCAGGTCAAATTCTCCCTTTGGTAGTATCTTATTCAAGCAGTT
ATCTACTACAGATTCGGAAGACGTCGTTAAAGTAGAATTCTGGTTATAGAGGTCATTTTC
AACTGAGGCATCTGAAAAATTCCCAAAATCATCACTAGAATCACTTTCTGCATCTAATGC
ATTTGTGACAGGTTCTATCTGATCTCTATCGCTCATTTGCTTGCTTTGAAAGAGGTGCCT
TTTTCTATCTTGCTACACCTTAAATTCTCGTTTGTGATACGCCTAACGTTTTTTTTTTTT
TTCAGTTTTGATAGCAATTCGCGAAACTTTTTGTAACATCTTCTCTTCTCGAAAAGCGAA
AATAGTAAACAATAACTTAAAGCGTATTGGTATTAATATATTTAGTTGTAGTAAAATCAT
TTCACCAAACACACATACATGCGCTATTTGTATTGAGAAA
Chr coordinates
Chr II from 207194-209224