Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NCL1 Systematic Name
YBL024W Alias
TRM4 Strain
S288c Description
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C at wobble position in response to hydrogen peroxide, causing selective translation of mRNA from genes enriched in TTG codon; loss of NCL1 confers hypersensitivity to oxidative stress; similar to Nop2p and human proliferation associated nucleolar protein p120 External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NCL1 YBL024W
ATGGCTAGAAGAAAGAATTTCAAAAAAGGGAACAAGAAGACTTTTGGTGCTCGTGATGAC
TCGAGAGCTCAAAAAAACTGGTCTGAACTGGTAAAGGAAAATGAAAAATGGGAAAAATAC
TATAAGACTTTAGCTCTTTTCCCAGAAGATCAATGGGAAGAATTTAAAAAGACATGTCAA
GCTCCACTTCCTCTAACTTTTAGAATTACAGGTTCTAGAAAGCATGCCGGTGAGGTCCTG
AATTTGTTTAAAGAAAGACATCTACCAAACTTGACTAATGTTGAGTTTGAAGGTGAGAAG
ATTAAGGCCCCTGTAGAATTACCTTGGTATCCAGACCATCTTGCTTGGCAATTGGACGTT
CCTAAGACGGTTATTAGAAAGAATGAACAATTCGCAAAAACTCAGAGATTTTTAGTTGTT
GAAAATGCCGTTGGTAATATCTCAAGACAAGAAGCCGTTTCAATGATTCCTCCAATCGTT
CTAGAAGTAAAACCTCATCACACTGTTTTAGATATGTGTGCTGCTCCTGGCTCCAAAACT
GCTCAATTAATCGAAGCCTTGCACAAGGATACAGATGAACCATCTGGTTTCGTTGTAGCT
AATGATGCCGATGCCAGAAGATCTCATATGTTGGTTCACCAATTGAAGAGATTGAACAGT
GCCAACTTGATGGTTGTCAACCATGACGCCCAATTCTTCCCACGTATCAGATTACATGGC
AACTCAAATAACAAGAATGATGTTTTAAAATTTGACAGAATCCTGTGTGACGTTCCATGT
TCTGGTGATGGTACCATGAGGAAAAATGTTAATGTTTGGAAAGACTGGAACACACAAGCA
GGTCTTGGTTTGCATGCTGTTCAGCTGAATATATTAAACAGGGGTTTGCATCTTCTAAAG
AACAACGGTAGATTGGTTTACTCAACCTGTTCTTTAAATCCTATTGAAAATGAAGCGGTT
GTTGCCGAAGCGTTAAGAAAGTGGGGTGACAAGATTAGATTAGTTAACTGTGATGATAAG
CTTCCTGGCCTAATAAGATCCAAGGGTGTATCCAAATGGCCTGTCTATGACAGAAATTTG
ACTGAGAAAACCAAAGGAGACGAAGGTACACTAGATAGTTTCTTTTCACCATCTGAAGAA
GAGGCATCGAAATTCAATTTACAAAATTGTATGAGGGTTTATCCTCACCAACAAAACACA
GGCGGATTTTTCATTACTGTTTTCGAAAAAGTCGAAGATAGCACTGAGGCGGCTACAGAG
AAACTATCTTCTGAAACCCCAGCTCTAGAGTCTGAAGGACCTCAAACAAAGAAAATAAAG
GTAGAAGAAGTCCAAAAGAAAGAAAGACTACCACGTGACGCGAACGAAGAGCCTTTTGTT
TTCGTTGATCCACAGCACGAAGCTTTAAAAGTTTGTTGGGATTTCTACGGCATCGATAAT
ATTTTCGACAGAAACACTTGTTTAGTGCGTAACGCCACTGGTGAACCAACAAGAGTGGTT
TACACTGTGTGTCCAGCATTGAAGGATGTTATTCAAGCGAATGACGATAGGTTGAAGATT
ATTTATTCTGGTGTAAAATTGTTTGTCTCTCAAAGAAGTGATATCGAATGTTCATGGAGA
ATCCAAAGTGAATCATTGCCAATAATGAAACACCATATGAAATCTAATAGAATTGTTGAA
GCTAATTTAGAGATGTTAAAACACTTGTTAATCGAATCTTTCCCTAACTTTGACGACATT
CGTTCGAAGAACATCGATAATGATTTTGTTGAAAAGATGACAAAATTAAGCTCTGGTTGC
GCCTTTATTGATGTGTCAAGAAATGACCCTGCCAAAGAAAACTTATTCTTGCCTGTGTGG
AAAGGCAACAAGTGTATCAATTTGATGGTTTGTAAAGAAGATACTCATGAGCTATTATAT
AGGATCTTTGGTATTGATGCGAATGCCAAGGCTACTCCAAGCGCTGAAGAAAAAGAAAAA
GAAAAAGAAACGACTGAATCTCCCGCAGAAACTACTACCGGAACCTCTACTGAAGCTCCT
AGCGCTGCTAATTGA Promoter Sequence
Download FASTA
>NCL1 YBL024W
ACATGTAGTGAGCGCCGATGAAGTACTCGCAGAAAAAATAGATAATGCTGTTCCTATACC
GTTCAAAACAAGGGAGGAGATAGATGCCGACGTGGAAAAAGATAGAAACGAAGGAGTTTT
CGAAGGTAATATCATTCCTGATATCGACCTACGTGTAGTACACTACTACGCCACGCAGTT
GTGTCTAAATAAGTATCCTCATTTGATTAACGCCTTTGATGAGACAAGCCTTATAACATT
GGGTTTACTCATCGAAAAGTGGGTAAAAGACTATCTAACCAGCATCCAGACAGAACAGGG
AAGGCAAAGTAAGGTAATCGGGAAGGGGCCATGCGAATTCATATCAAAACATATTGATTA
TAGGCATGCGCCAGGTAATATCTGAATGTAGCAAAAACCTGGCTTTTGCGGCTGGGGAGG
ATGGAAGGCTTTTGTAGGCTATTATCTACTCGAGGAAGGAACGTTAGAATATCTCCATTT
TTCACGCAAAATGTGGTTCTGAGTTAATGCGTGTGCTGAAGCATAACATGAGTTATTCCC
TGTATGTATGTACAGTATTTCAATTTCGCAGACCGTGGGTTACATATGTGAGCGATTAGG
AAGTAGTGAAGTAATTATGGCAAGTCTAGAGGTCCGGCTGATCCCTTGCGGTGCTGAAGT
AACGAAACCGCGCGCATATCTTTTGGAAGAGATTAATTTGCACTGAATTTTCAAACTTAA
TTAGCGAGAAGAAGTAGATGCATTTCAATTATGCCAAAAGCAGTATTTATTACTTCTTAT
AGAATATAGTATCACTTACGCTCATTTAGTGTACCCACTTACGTATTAAATGACGTACTT
TTTTTTTGTCCTCTTCTGTAGCTTTTTTTCACTTTGAAAAATTTAGCGCTGAGTTCTTCC
AAAGACGTCAAATCACCTACTATAGTTAAAAACATATTACTTATACTAGTTCTAACACTT
CCTTTTATCTACACTGTAATCCGAAGAATACACTATAAGG
Chr coordinates
Chr II from 172534-174588
