Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name PRS4
Systematic Name YBL068W
Strain S288c
Description 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS4 has a paralog, PRS2, that arose from the whole genome duplication; a missense mutation in the conserved residue R196 of its human homolog PRPS1 is pathogenic
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>PRS4 YBL068W
ATGAATTCAGAGTCTCGAGAAGATATGGCTATAAATAGTATCAAATTGCTAGCGGGAAAC
TCCCATCCTGATTTGGCTGAACAAATATCGAAAAAGTTAGGTATTCCACTTTCCAAAGTT
GGTGTGTACCAGTATTCTAATAAAGAAACCTCTGTCACCATAGGTGAGAGCCTTCGCGAC
GAAGATGTGTATATTATCCAAACTGGAATAGGTGAACAAGAAATTAATGATTTCTTGATG
GAATTATTAATTTTAATTCATGCTTGCAAAATTGCATCTGCAAGAAAGATCACTACTGTA
ATACCCAATTTTCCATATGCAAGACAAGACAAGAAAGATAAATCCCGGGCGCCCATTACC
GCAAAGTTGGTTGCCAATTTATTGCAAACTGCTGGTGCTGATCATGTCATCACAATGGAT
CTCCATGCCTCCCAAATTCAAGGGTTTTTCCATATCCCGGTTGACAACCTATATGCAGAA
CCAAGTGTTTTAAATTATATTAGAACGAAAACAGATTTCGACAATGCTATTTTGGTGTCG
CCTGATGCAGGTGGTGCTAAGAGAGTAGCTGCTTTGGCTGACAAGTTAGATTTAAATTTT
GCTTTGATTCACAAAGAGAGGCAAAAAGCTAACGAGGTTTCAAAAATGGTGCTTGTTGGT
GATGTTACCAATAAATCATGTTTATTAGTTGATGATATGGCGGATACTTGTGGTACGTTG
GTAAAAGCTTGTGATACGTTGATGGAGCATGGTGCCAAAGAAGTTATAGCTATTGTTACA
CACGGTATTTTCTCCGGTTCAGCAAGAGAAAAGCTAAGAAATAGTAGATTGTCTAGAATT
GTTTGCACAAATACCGTTCCGGTAGATTTGGATTTACCTATTGCTGACCAGATCGATATT
AGTCCCACGTTCGCTGAAGCTATAAGAAGACTACACAATGGTGAATCCGTGTCATATTTG
TTCACCCATGCTCCAGTATAG
Promoter Sequence
Download FASTA
>PRS4 YBL068W
TACAGAAAAAACTAGTGATTGTAACGTCTGCAAATGGGCCCCAAGTTTTACAGGAGAAAT
TTCCTGATCTGGCTGATGAAATGATTTTCATCGATTACTTAACGTGTAGGGGTAAATCTA
GTAAACCACTAAGAAAAATGCTCGAAGAAAAGAAAATTTCTCAGTATGATCCGGTCGAGG
ATAAGGAAACTATACTTAACTATAATGAGGGGAAGTTCGATGTTGTACTCGATTTTGTCG
GTGGTTACGATATTTTGAGTCATTCTAGTTCATTGATTCACGGCGGTGGTGCGTACGTAA
CCACTGTAGGTGATTACGTTGCCAATTATAAAGAAGACATTTTCGATTCATGGGATAACC
CAAGTGCCAATGCAAGAAAAATGTTCGGGTCTATTATCTGGTCATATAACTACACACATT
ACTATTTTGATCCGAATGCAAAGACGGCTTCCGCCAATAATGATTGGATTGAGCAATGTG
GCGACTTTTTGAAGAACGGTACTGTAAAATGTGTCGTCGACAAAGTTTATGACTGGAAAG
ACCATAAAGAAGCATTTTCTTATATGGCCACTCAACGTGCCCAAGGAAAGTTAATCATGA
ACGTCGAAAAATTCTAGATACCCACTTACATTTACAATATGTTTTATTTTTAAACTTAAT
GAACTTCATAATTTAATGCTTAATATTTTCCCCCTCCCACCTTCTCCTGGCGTTCTCTGT
ACGTACATAACCATTTATTTTAATATATAATCAAATATTGTAACAATTGAAGCAGATGAG
TCTCGCTCCTTAGTTAAGCACGTGCCGATGATATCAATTGGATTTGTTAGCAAATCAGCC
TTGCTGCTCGATTCTCTGCTTTTTTTTTACTTCTCGGTCATTGAAAAATCCTGACGAAAA
TATTTCAAGGTCCTATATGGTCATCGACCTTGAGCATGTGGTAGACTACATAATGCACAT
AGACTCTCAGCTTCAACTCCACAAGGCTTCTCCAGCAAAA
Chr coordinates Chr II from 92414-93394
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