Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SCS22
Systematic Name
YBL091C-A
Strain
S288c
Description
Protein involved in regulation of phospholipid metabolism; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect the ER and plasma membrane (PM); regulates PM PI4P levels by controlling access of the Sac1p phosphatase to its substrate, PI4P; human VAP homolog; similar to D. melanogaster inturned protein; SWAT-GFP and mCherry fusion proteins localize to the cytosol; SCS22 has a paralog, SCS2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SCS22 YBL091C-A
ATGAGAATAGTGCCAGAAAAGCTGGTGTTCAAGGCTCCCCTTAATAAACAATCAACAGAG
TATATAAAGCTCGAGAACGATGGTGAAAAGAGAGTTATATTTAAAGTGAGGACTAGTGCT
CCCACAAAGTATTGTGTGAGGCCCAATGTGGCCATCATAGGTGCTCATGAAAGTGTAAAT
GTCCAAATTGTTTTCCTTGGATTACCCAAGTCAACCGCTGACGATGAAATGGACCAAAAA
CGAGACAAATTCTTGATCGTTACACTTCCTATCCCGGCAGCTTACCAAAACGTGGAGGAT
GGCGAGCTGTTGTCCGATTGGCCTAATCTGGAAGAGCAGTACAAAGATGACATAGTCTTC
AAGAAGATCAAAATATTTCACTCCGTGTTACCGAAAAGAAAACCGTCTGGAAACCACGAT
GCAGAATCAGCAAGAGCGCCATCAGCAGGTAACGGGCAAAGTCTGAGTTCCAGAGCATTG
CTTATCATCACCGTTATCGCATTGCTCGTCGGCTGGATATACTACTGA
Promoter Sequence
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>SCS22 YBL091C-A
TAGCGATGGAGGATCCCAAATCTCAAGGTATTGGGTTTCCAACGGGTCTCTCTCTCAACC
ATTGTGCTGCACATTTCACACCCAATGCAGGCGACAAAACCGTTCTGAAATACGAAGACG
TGATGAAGGTAGATTATGGTGTGCAGGTAAACGGTAACATCATTGATTCTGCCTTTACTG
TTTCCTTTGATCCACAATACGATAACCTGCTAGCCGCTGTAAAGGACGCTACTTACACGG
GTATTAAAGAAGCGGGTATCGATGTGAGATTAACCGACATCGGTGAAGCCATCCAAGAAG
TTATGGAATCCTACGAAGTGGAAATCAATGGTGAGACTTACCAGGTTAAACCTTGTCGTA
ATCTATGTGGCCACAGTATCGCACCATATCGTATCCACGGCGGTAAATCCGTTCCCATCG
TCAAAAATGGGGACACTACAAAAATGGAGGAAGGTGAGCACTTTGCCATTGAAACTTTTG
GTTCTACTGGTAGAGGTTATGTTACTGCCGGTGGGGAAGTTTCTCATTATGCCAGATCTG
CTGAAGACCATCAGGTAATGCCCACGTTAGACAGCGCCAAGAACTTGTTAAAAACGATAG
ACCGCAACTTTGGGACTTTACCGTTCTGTCGCCGATACCTAGACAGACTTGGCCAAGAGA
AATACTTATTTGCGTTGAATAACTTGGTTAGACACGGTTTAGTACAGGATTATCCACCAT
TGAACGATATCCCCGGATCCTACACTGCACAATTCGAACACACCATCTTGTTGCATGCTC
ACAAAAAGGAAGTCGTTTCGAAAGGTGATGACTACTGAGGTAAAATGCGCTTTCAAATGG
CCTCCTCACTAGGTATATGAATACTGTTGTAGTTATATAGATAGTTTAATATGGCTTGCC
GCCCGTTTAGAATGATGCATTACCTTATATAAGACCTATGGGGGTCTCAAACAGTGGTAT
GACGACAGATAATATAAGCACTAGTTCAGACGAGTAAACA
Chr coordinates
Chr II from 47058-46565,47180-47147