Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CKS1
Systematic Name
YBR135W
Strain
S288c
Description
Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p (aka Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters; human homologs CKS1B and CKS2 can each complement yeast cks1 null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CKS1 YBR135W
ATGTACCATCACTATCACGCCTTCCAAGGCAGAAAGCTTACTGACCAAGAAAGAGCACGC
GTGTTGGAGTTTCAAGATTCCATTCACTATTCTCCGCGGTACTCAGACGATAACTATGAG
TACAGGCATGTGATGTTACCTAAGGCCATGCTAAAAGTTATCCCATCTGATTACTTCAAT
TCGGAAGTGGGGACCCTGCGTATATTAACAGAAGACGAATGGAGAGGCCTCGGCATCACA
CAGTCTTTGGGGTGGGAACATTATGAATGCCATGCGCCAGAACCACACATTTTGCTATTC
AAAAGGCCGCTGAACTACGAGGCCGAGCTGAGGGCAGCGACCGCTGCTGCTCAACAGCAA
CAGCAACAGCAGCAACAGCAGCAACAACAACAACAGCAACATCAAACACAATCGATTTCG
AACGATATGCAAGTTCCACCCCAAATCTCCTAG
Promoter Sequence
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>CKS1 YBR135W
GGCGCCAATATTAGCTTATTGATTCCAACAAACCTCGCGTACTTACATTCGTTTAGAAGG
ACCTTTAAGCCAAGATCTCTTACATTTGGATCGCGACTCTCCAGCTCCAGCCAAGAGGAT
AACAGCCCTATGTAAGACGGCGTATCGTCATTGTCTAGCTTCTTGACGTTGAACGGGGGT
ATACAGATATCCTGCAACTGCGGTTCAGGAATTTGAAGCGGTTTCCAGTTCTGTATGGAT
TGTCTTTGGAAATCTTTGAAAACTTGCCCAACTATTTCCTTATATCTTGGCGTTGTTATA
GGAAGCAAAACGTAATCATAGTTACTAGGCAGTTCTGGTGAATGACTAGAGACATTTTCT
AGGAAACGTGACTTTTTGCTGTGCTGTTTATGATTAAAGCCTGGTTTGACACCAACAAAT
ACGTTGCTATGCATATGCAAACTGAACCCTTTGTATATATAAAAATTATATGTATAAAAG
AAGAGGAACGTCCGCACAATTCCACACACACACACACACACACGCTTTCACACACGCAAT
TTGAAATAGCTCCTATAGGGCTTGGGAATAGGATCACAAGTCACTCGAAATATACCATTT
TTTCTATCACACATACACATTGTATAAAGCCATTTGTTTCAAAAAAATATAAAAACACTG
CGCAGCGTGCTGTTTCGGGTTCCATTTGTGATTGTTTATTTTTCTTTTGGTTTAGCTCAG
TGCAAAACGAGGGCTCGAAGAATTTTCAGATAAAACAGTACTCGAGCCCTGAGATCTGTT
TTAGGGTCTAAAAGGCGGGTTATAAAAATATGTCAGGTGATTTTTTTTTCTCGTGGTATG
AGATAAATAAAGAATGGAGCTTTTATGCATGAAAGGACAGCGGATGGCAGTAGAGCAGAC
ATCAGTAGCATTCATTACAACTCTGTCGTAAGTTCTTGGAACTGCTGGCCGCGTTGGATA
CAACTAGATTGACACGCACTTACTCTCGTCTTACAGTACT
Chr coordinates
Chr II from 504854-505306