Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name MEC1
Systematic Name YBR136W
Alias ESR1, RAD31, SAD3
Strain S288c
Description Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>MEC1 YBR136W
AGGTGATTTTTTTTTCTCGTGGTATGAGATAAATAAAGAATGGAGCTTTTATGCATGAAA
GGACAGCGGATGGCAGTAGAGCAGACATCAGTAGCATTCATTACAACTCTGTCGTAAGTT
CTTGGAACTGCTGGCCGCGTTGGATACAACTAGATTGACACGCACTTACTCTCGTCTTAC
AGTACTATGTACCATCACTATCACGCCTTCCAAGGCAGAAAGCTTACTGACCAAGAAAGA
GCACGCGTGTTGGAGTTTCAAGATTCCATTCACTATTCTCCGCGGTACTCAGACGATAAC
TATGAGTACAGGCATGTGATGTTACCTAAGGCCATGCTAAAAGTTATCCCATCTGATTAC
TTCAATTCGGAAGTGGGGACCCTGCGTATATTAACAGAAGACGAATGGAGAGGCCTCGGC
ATCACACAGTCTTTGGGGTGGGAACATTATGAATGCCATGCGCCAGAACCACACATTTTG
CTATTCAAAAGGCCGCTGAACTACGAGGCCGAGCTGAGGGCAGCGACCGCTGCTGCTCAA
CAGCAACAGCAACAGCAGCAACAGCAGCAACAACAACAACAGCAACATCAAACACAATCG
ATTTCGAACGATATGCAAGTTCCACCCCAAATCTCCTAGCTTTGATATACTCTAATTACT
GAAATTGAATTCCTTTTCAAGGCTCCATAACTATATGGAGCATACTATGTACTTATCATA
ATAAAGAATAAACAAACAAGCAAACAAAAAAAAAAAAAACTATGGATCATAGTTTTCACC
AACAAGCATTAGAATACAAATAAAATTTATATAGTGAATATCCTTCAAATAAATTTCTTC
TTTCCCTTATAAATCAAATAGATGGAACGCACGCTCCAAAACTAGTCAACTAGAAAAAAA
TACCCGCCGACGGACAATTTTGAAGAGAGATGATTAATGAAGACAAAGTGAGGCTGGACA
ACAAGAACGACATACACCGCGTAAAGGCCCACAAGACTGC
Chr coordinates Chr II from 505668-512774
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