Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MEC1 Systematic Name
YBR136W Alias
ESR1, RAD31, SAD3 Strain
S288c Description
Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>MEC1 YBR136W
ATGGAATCACACGTCAAATATCTTGACGAATTGATATTGGCAATAAAAGACCTGAACTCG
GGGGTGGATTCAAAGGTGCAGATTAAAAAAGTGCCCACGGATCCATCTTCTTCTCAGGAG
TACGCCAAGAGTTTAAAGATCCTGAACACCCTCATAAGAAACCTAAAAGATCAAAGAAGG
AACAATATCATGAAAAATGATACTATATTTTCGAAAACAGTTTCCGCCCTTGCCTTATTG
TTGGAGTACAACCCCTTCTTGCTTGTTATGAAGGATTCCAACGGGAACTTTGAGATACAA
AGGCTGATAGATGATTTCCTCAACATATCCGTTCTGAACTATGATAATTACCACAGAATA
TGGTTTATGAGGCGAAAATTAGGCAGCTGGTGCAAAGCATGTGTCGAATTTTACGGAAAA
CCTGCTAAGTTTCAGCTTACTGCACATTTTGAGAACACCATGAATCTTTACGAACAGGCC
TTGACTGAAGTCTTGTTGGGCAAGACTGAGCTTCTCAAATTTTATGACACCTTGAAGGGT
CTATACATTCTTTTATACTGGTTCACTTCGGAGTATAGTACTTTTGGGAACTCTATAGCA
TTCTTAGATTCTTCTTTGGGGTTCACGAAATTTGACTTTAACTTCCAACGATTAATCAGG
ATTGTTCTTTACGTCTTTGATTCCTGCGAACTAGCAGCACTAGAATATGCCGAAATCCAA
CTCAAATATATTTCTCTAGTTGTGGACTATGTTTGCAATAGAACAATTTCCACAGCCCTG
GATGCCCCAGCGTTAGTTTGTTGTGAACAATTAAAGTTTGTATTGACTACTATGCATCAT
TTTTTGGATAACAAGTATGGGCTCTTGGATAATGACCCCACTATGGCCAAAGGAATTCTT
CGACTATATTCTCTTTGCATTTCTAACGATTTCTCAAAATGCTTTGTAGACCACTTCCCA
ATTGACCAGTGGGCAGATTTTTCACAAAGTGAACATTTTCCGTTCACGCAGTTGACTAAT
AAAGCTCTCTCGATTGTATATTTTGATTTGAAAAGAAGGTCCCTACCTGTTGAAGCTTTA
AAGTACGATAATAAGTTCAACATCTGGGTATACCAATCGGAGCCGGACTCGAGCTTGAAA
AATGTCACTTCTCCCTTTGATGATCGATATAAGCAGCTGGAAAAGCTAAGGTTGCTAGTA
CTAAAGAAGTTTAACAAGACAGAAAGAGGAACTTTGCTCAAATACCGCGTGAACCAGCTA
AGTCCTGGATTTTTTCAAAGAGCTGGAAACGATTTCAAGCTAATTTTAAATGAAGCATCT
GTATCCATTCAAACTTGTTTCAAGACAAACAATATAACAAGGCTAACATCATGGACTGTA
ATTCTCGGACGTCTAGCCTGTCTAGAATCAGAGAAGTTTTCCGGCACTCTGCCAAATTCC
ACAAAGGATATGGATAATTGGTATGTTTGTCATTTATGCGATATTGAGAAAACTGGCAAC
CCTTTCGTGCGAATAAATCCAAATAGACCAGAGGCTGCGGGTAAATCAGAAATCTTCAGG
ATACTTCATTCAAACTTTCTATCTCACCCAAATATAGATGAATTTAGCGAATCTTTGTTA
AGTGGCATCTTATTTTCTCTACATAGGATATTTTCACACTTTCAACCTCCAAAACTTACA
GATGGAAACGGTCAAATCAATAAGAGCTTTAAACTGGTACAAAAGTGCTTTATGAATTCT
AACAGATACCTACGTTTATTAAGTACTAGAATTATACCTTTATTCAATATATCAGACTCT
CATAATTCCGAAGATGAACACACTGCCACGCTGATAAAGTTTCTACAATCTCAAAAATTG
CCAGTGGTGAAAGAAAATTTAGTCATTGCTTGGACACAATTAACATTGACGACTTCTAAT
GATGTATTTGATACACTACTTTTGAAACTGATTGATATTTTCAATTCTGATGATTATAGT
TTACGAATAATGATGACTTTGCAAATTAAAAATATGGCCAAAATTTTAAAGAAAACACCA
TATCAATTACTATCGCCTATTTTACCTGTATTACTAAGACAGTTGGGAAAAAACCTCGTG
GAAAGAAAAGTTGGCTTTCAAAATTTAATAGAATTATTGGGATATTCTTCAAAAACAATT
CTCGATATTTTCCAGAGATATATCATCCCTTATGCAATTATTCAATATAAGAGCGATGTG
CTAAGTGAAATTGCTAAGATTATGTGTGATGGCGATACAAGTTTAATTAACCAAATGAAG
GTTAATTTACTGAAAAAAAACAGTAGGCAAATATTTGCCGTAGCTTTGGTAAAACACGGA
TTATTTTCTTTGGATATCTTGGAAACCCTTTTTTTAAATAGGGCTCCAACTTTTGACAAA
GGATATATAACTGCATACCTTCCCGATTATAAAACTTTAGCTGAAATAACGAAGCTCTAC
AAAAACAGCGTTACTAAAGATGCAAGTGACAGCGAGAATGCTAATATGATTTTATGCTCT
TTGCGATTTTTAATCACCAATTTTGAAAAAGACAAAAGGCATGGTTCGAAGTACAAAAAT
ATCAATAACTGGACGGATGATCAGGAACAAGCGTTCCAAAAGAAACTACAGGATAATATC
TTAGGTATTTTCCAAGTTTTTTCGAGTGACATACATGATGTTGAAGGCCGCACCACTTAC
TACGAAAAGTTAAGGGTTATCAATGGCATTTCTTTTCTTATCATATATGCCCCCAAAAAA
TCAATAATTTCCGCATTAGCCCAGATTAGTATTTGTTTGCAAACAGGACTTGGGCTTAAG
GAAGTTCGATACGAGGCCTTTAGATGTTGGCATCTGTTAGTTCGCCATCTAAATGATGAA
GAACTCTCTACTGTTATAGATAGCTTAATTGCATTCATACTTCAAAAGTGGTCTGAGTTC
AACGGAAAACTTCGAAATATAGTGTACAGTATACTGGATACCTTAATCAAAGAGAAATCG
GACCTGATTTTGAAATTAAAACCTTACACTACTTTGGCTTTAGTAGGCAAGCCTGAATTA
GGTATTTTAGCTCGTGATGGCCAATTTGCAAGAATGGTGAATAAAATAAGAAGTACCACG
GACCTTATACCCATATTTGCTAATAACTTGAAAAGTAGTAACAAGTATGTCATAAACCAA
AATTTAGACGATATAGAGGTATATCTTCGGAGAAAGCAGACAGAAAGATCGATTGATTTT
ACACCAAAGAAGGTTGGGCAAACTTCTGATATAACATTAGTTTTGGGTGCTTTATTAGAC
ACTTCTCATAAGTTTAGAAATTTAGACAAGGACCTATGCGAGAAGTGCGCCAAATGTATC
AGTATGATTGGTGTTTTAGACGTTACAAAGCATGAGTTTAAAAGAACAACATATTCAGAA
AACGAAGTTTATGATTTGAATGATAGTGTTCAAACTATTAAGTTCTTGATATGGGTCATA
AATGATATCCTCGTTCCTGCGTTTTGGCAAAGTGAGAATCCCAGCAAGCAATTGTTTGTT
GCCCTTGTCATACAGGAATCATTAAAATATTGCGGGCTAAGTTCAGAGTCATGGGATATG
AACCATAAAGAATTATATCCAAATGAAGCCAAACTATGGGAAAAGTTTAACTCTGTCTCC
AAGACAACCATCTATCCGCTTTTATCTTCCTTGTATCTTGCGCAATCATGGAAAGAATAT
GTCCCGCTAAAATATCCTTCTAATAACTTCAAGGAAGGATACAAAATTTGGGTGAAAAGG
TTTACATTGGATTTATTGAAAACAGGTACAACAGAAAATCATCCATTACACGTGTTTTCC
TCTTTGATTAGGGAAGATGATGGCTCACTATCAAATTTTTTGCTACCTTATATTTCTCTG
GACATTATTATCAAGGCAGAAAAAGGAACTCCATACGCTGATATTTTAAACGGGATTATT
ATTGAATTTGACAGCATTTTCACGTGCAATCTGGAAGGAATGAATAACTTGCAAGTGGAT
TCGTTAAGAATGTGCTATGAATCCATCTTCAGAGTTTTCGAATATTGCAAAAAATGGGCA
ACTGAGTTTAAACAAAATTACAGTAAACTACACGGCACTTTTATCATTAAAGATACGAAA
ACAACTAACATGCTTTTGAGAATAGATGAGTTTTTGCGAACAACCCCTTCAGATTTGCTA
GCTCAACGCTCCTTAGAGACGGATTCTTTTGAAAGGTCTGCTCTATACCTTGAACAGTGC
TATCGACAGAATCCTCACGATAAGAACCAAAATGGACAACTACTGAAAAATTTACAAATC
ACATACGAAGAAATAGGAGACATTGACTCACTCGATGGTGTACTGAGAACCTTTGCTACA
GGAAACTTGGTTTCTAAAATTGAAGAATTGCAATATTCTGAAAACTGGAAACTCGCACAA
GACTGCTTTAATGTCCTCGGCAAATTTTCAGATGACCCCAAAACTACAACCAGGATGCTA
AAGTCTATGTATGACCACCAATTGTATTCTCAAATAATATCGAACTCTTCGTTCCATTCT
TCAGACGGAAAAATTTCTTTGTCTCCAGATGTGAAGGAATGGTACAGCATAGGTCTTGAA
GCTGCAAATCTAGAAGGCAATGTTCAAACTTTGAAAAATTGGGTAGAACAAATAGAGAGT
TTAAGAAATATTGACGATAGAGAAGTACTTTTGCAGTACAATATTGCGAAAGCTTTAATT
GCCATCTCAAACGAGGATCCATTAAGGACTCAAAAATACATCCACAATTCCTTTAGGCTT
ATCGGAACAAATTTTATAACGTCATCTAAAGAGACGACGCTGCTAAAGAAACAGAATTTA
TTGATGAAATTACACAGTTTATATGACCTCAGTTTTTTATCTTCTGCGAAAGATAAGTTT
GAATACAAAAGTAACACTACCATACTCGATTATCGAATGGAACGTATTGGGGCTGACTTC
GTGCCAAATCATTACATATTGTCAATGAGAAAGTCATTTGACCAATTGAAAATGAATGAA
CAAGCAGACGCTGACTTAGGAAAAACATTCTTCACTTTAGCCCAATTGGCGAGAAACAAC
GCTAGGCTAGATATAGCCTCCGAATCATTAATGCATTGTTTGGAAAGGCGGTTGCCTCAG
GCAGAGTTGGAGTTTGCTGAAATACTATGGAAGCAAGGTGAGAATGATAGAGCCTTAAAG
ATAGTGCAAGAAATACATGAAAAGTATCAAGAAAATTCCTCGGTTAATGCTCGCGATCGT
GCCGCCGTGCTATTAAAGTTTACTGAATGGTTAGACCTTTCGAACAATTCAGCGTCCGAA
CAAATTATTAAACAATATCAGGATATTTTTCAGATTGATTCTAAATGGGATAAACCATAT
TACTCTATTGGCTTATACTATAGTAGACTACTTGAGCGCAAAAAAGCAGAGGGTTATATT
ACTAATGGTCGTTTTGAGTACAGGGCAATATCTTACTTTTTATTGGCATTTGAAAAGAAC
ACTGCTAAAGTAAGAGAAAATTTGCCCAAAGTTATCACGTTTTGGCTAGATATTGCGGCC
GCATCAATTTCTGAAGCTCCTGGAAACAGAAAGGAAATGCTGAGTAAGGCTACGGAAGAT
ATATGTAGTCATGTTGAAGAAGCGCTGCAGCATTGTCCCACTTATATTTGGTACTTTGTT
TTGACTCAGTTGTTATCTAGGTTATTACATTCTCATCAATCATCGGCCCAGATAATAATG
CACATACTGCTAAGTTTGGCTGTTGAATACCCCTCTCATATTTTATGGTATATCACAGCC
CTTGTAAATTCCAATTCTTCAAAAAGAGTTCTTCGTGGTAAGCATATTTTAGAAAAGTAT
AGACAACATTCGCAAAATCCTCATGATCTAGTTTCTAGTGCATTGGATTTAACGAAAGCA
TTAACTCGTGTCTGTTTGCAAGATGTCAAAAGCATTACAAGTAGATCAGGCAAATCTTTA
GAAAAAGACTTCAAATTTGACATGAACGTGGCCCCATCTGCAATGGTTGTTCCAGTAAGA
AAAAATTTAGACATCATTTCACCACTAGAGTCTAACTCAATGAGGGGCTATCAACCATTT
AGGCCGGTTGTTTCTATAATTAGATTCGGATCATCTTATAAAGTGTTTTCTTCATTAAAG
AAGCCAAAACAATTGAACATAATAGGTTCAGATGGCAACATTTATGGGATCATGTGTAAG
AAGGAAGATGTCCGACAAGATAACCAATATATGCAGTTCGCCACAACAATGGATTTTCTT
CTGAGTAAGGACATAGCTTCAAGAAAAAGAAGCCTGGGCATAAATATTTACTCCGTACTA
TCTCTTCGAGAAGACTGTGGGATATTGGAAATGGTACCGAATGTTGTAACTTTAAGATCT
ATTCTTTCTACAAAGTACGAAAGTCTGAAAATTAAGTATAGCCTGAAAAGTCTACATGAT
AGGTGGCAGCACACCGCAGTAGATGGAAAACTCGAGTTTTACATGGAACAGGTAGATAAA
TTTCCTCCAATCTTGTACCAATGGTTTTTAGAAAACTTTCCTGATCCAATCAATTGGTTC
AACGCCAGGAATACGTATGCCAGATCTTACGCCGTCATGGCAATGGTTGGCCATATATTA
GGTCTAGGTGATAGGCACTGTGAAAACATATTACTAGATATACAGACGGGTAAAGTTCTT
CATGTAGACTTCGACTGTTTATTTGAGAAAGGCAAAAGGTTACCTGTCCCAGAAATTGTT
CCCTTCAGACTAACACCAAATTTATTGGATGCGTTGGGCATAATTGGGACAGAAGGAACA
TTTAAGAAGTCTAGTGAAGTCACGTTGGCTTTAATGAGAAAAAATGAAGTAGCGTTGATG
AATGTGATCGAAACAATTATGTACGATAGAAACATGGACCACTCAATTCAAAAAGCGCTA
AAGGTCTTAAGAAACAAAATCCGCGGTATAGATCCGCAGGATGGCCTGGTATTGAGTGTT
GCTGGCCAAACAGAAACATTGATCCAAGAAGCAACATCAGAAGACAATCTAAGCAAGATG
TATATTGGTTGGCTTCCATTTTGGTAA Promoter Sequence
Download FASTA
>MEC1 YBR136W
AGGTGATTTTTTTTTCTCGTGGTATGAGATAAATAAAGAATGGAGCTTTTATGCATGAAA
GGACAGCGGATGGCAGTAGAGCAGACATCAGTAGCATTCATTACAACTCTGTCGTAAGTT
CTTGGAACTGCTGGCCGCGTTGGATACAACTAGATTGACACGCACTTACTCTCGTCTTAC
AGTACTATGTACCATCACTATCACGCCTTCCAAGGCAGAAAGCTTACTGACCAAGAAAGA
GCACGCGTGTTGGAGTTTCAAGATTCCATTCACTATTCTCCGCGGTACTCAGACGATAAC
TATGAGTACAGGCATGTGATGTTACCTAAGGCCATGCTAAAAGTTATCCCATCTGATTAC
TTCAATTCGGAAGTGGGGACCCTGCGTATATTAACAGAAGACGAATGGAGAGGCCTCGGC
ATCACACAGTCTTTGGGGTGGGAACATTATGAATGCCATGCGCCAGAACCACACATTTTG
CTATTCAAAAGGCCGCTGAACTACGAGGCCGAGCTGAGGGCAGCGACCGCTGCTGCTCAA
CAGCAACAGCAACAGCAGCAACAGCAGCAACAACAACAACAGCAACATCAAACACAATCG
ATTTCGAACGATATGCAAGTTCCACCCCAAATCTCCTAGCTTTGATATACTCTAATTACT
GAAATTGAATTCCTTTTCAAGGCTCCATAACTATATGGAGCATACTATGTACTTATCATA
ATAAAGAATAAACAAACAAGCAAACAAAAAAAAAAAAAACTATGGATCATAGTTTTCACC
AACAAGCATTAGAATACAAATAAAATTTATATAGTGAATATCCTTCAAATAAATTTCTTC
TTTCCCTTATAAATCAAATAGATGGAACGCACGCTCCAAAACTAGTCAACTAGAAAAAAA
TACCCGCCGACGGACAATTTTGAAGAGAGATGATTAATGAAGACAAAGTGAGGCTGGACA
ACAAGAACGACATACACCGCGTAAAGGCCCACAAGACTGC
Chr coordinates
Chr II from 505668-512774
