Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
RTC2
Systematic Name
YBR147W
Alias
RRT11, YPQ3
Strain
S288c
Description
Putative vacuolar membrane transporter for cationic amino acids; likely contributes to amino acid homeostasis by exporting cationic amino acids from the vacuole; positive regulation by Lys14p suggests that lysine may be the primary substrate; member of the PQ-loop family, with seven transmembrane domains; similar to mammalian PQLC2 vacuolar transporter; RTC2 has a paralog, YPQ1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RTC2 YBR147W
ATGAAGCTGATCCCAATTATTTTGAATGCTAAGAATCTCAGTGGGATGGCTGGATCCATA
TCAATATGCTGTTGGATTGTTGTGTTTGTACCACAGATTTATGAAAACTTCCGAAGACAG
TCTGCGGAGGGATTATCACTGCTTTTCATTGTGTTGTGGCTATTAGGTGATATATTTAAC
GTCATGGGAGCTATGATGCAAAATTTACTCCCAACCATGATAATTTTAGCTGCTTACTAT
ACATTGGCAGATTTAATTTTGTTAATACAGTGCATGTGGTATGACAAGGAGAAGAAGAGC
ATTTTACAAGAAGTCAAGAAAAATGTTGATCCTGTGCATTTGCCTCCAGCAAACCCCATA
AATGAGACTGTCTTACAAGACGTTTTTAATGAATATGAGCCACTTTTGCCAAGGATAGAA
GAAGAAGATAGCCAATCGTATAGCTCGCTTGAGCTTGGCAGAACAATAGTCGTAAAGGAA
AGAGAGAATTTTTTCAATGACTTCTTAATTGTTTCAGGTGTACTTATTGCCGGAATTTTG
TCATGGTATATATCTTACTGTTCCGGCCTAGATAACGGTATTCCTAAAAAAAAACCTGCG
TTCGAACAGATTAATTTACCTGCACAAATTTTAGGGTATTTAAGTGCGATACTGTACTTG
GGCTCTAGGATCCCTCAGATTGTTCTTAACTTCAAAAGAAAATCATGCGAAGGAGTCTCA
TTCCTATTCTTTTTATTTGCATGCTTAGGGAACACTTCTTTCATAATCTCAGTGCTCTCA
GCATCTTGGCTTATCGGTAGCGCTGGTACGCTGTTGATGGACTTCACAGTTTTTATTCAA
TTTTTCCTTTACGCCAAACCTAAATACGAGAAAATACTAATAGATAATTAA
Promoter Sequence
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>RTC2 YBR147W
CTACTGTATATGTTGAATAAACTTCACAACATTGATCCTCAACTTACTAATGATGAAATC
ACATCCGAACTATCCCAATATTATAAAAAAAGTTCAATGCTTTCCAATAATATCAAAATC
AAAACTTTAGATGAGTTTGGAAGAAGTATAGCCGTTGGAAAAAGGAAAAGTTCCACTGCG
AAAGTATTCGTTGTTAGAGGTACAGGTGAGATATTAGTTAATGGTCGACAATTGAATGAT
TACTTCCTTAAGATGAAAGACAGAGAATCAATCATGTATCCACTTCAAGTGATCGAATCA
GTTGGAAAGTACAATATTTTTGCGACAACGTCTGGAGGCGGACCTACGGGTCAGGCTGAA
TCAATCATGCACGCCATTGCGAAAGCTTTGGTTGTGTTCAATCCATTATTAAAATCCAGA
CTACATAAAGCTGGCGTCTTAACAAGAGATTACAGGCACGTCGAAAGAAAGAAGCCAGGA
AAAAAGAAGGCAAGAAAGATGCCAACATGGGTCAAGAGATAGTCTTAGTGCATCTTGTTA
CCTCAATTTCGAACGGAAGCGTGCGTGCTCTGAGTTTTTTGACACATGCCAGAAGAAACG
TTATATATTTTGCATACAACGCCGCCCAGCATTAGAAGCACAACTCTCGTTCGTTATTCC
TGTAAATAAAGTTATATGTATTCGAATATTGCTCAGTTAGTATTTTCTTCTACTTACTGC
ACATAATACTTCATCTTTTTTTTCCTCTCACCCGCAAAGCAAAGGGGCCTTGCAGCAATG
ACTCAAATTCCATTGGAAAAAAGAAGGAGATGATAAGATGCAAATCAGAATAGATTTTAC
TATGACCGTTACATGTAAAAAGAGTCATAATATAAACCATAAATACTACAAATAACACCG
GGTTCAGGCATATAAATAAACTATTCTCCTGTAATATCCCACAATATTTTGTTATAACCC
AGACGTAATAGCCTCAAGCGAGCATCCCTAAATTTCTGCC
Chr coordinates
Chr II from 536575-537465