Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PCH2
Systematic Name
YBR186W
Strain
S288c
Description
Hexameric ring ATPase that remodels chromosome axis protein Hop1p; nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in rDNA; required for meiotic double-stranded break formation
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PCH2 YBR186W
ATGAGCTACATAGTTGACCTACAAGTGCGAGGATCATCTCTGAGGGTTATCAAATGTATG
TTTAGAGAGGATGAGCAAATTTCTTCTCTACATTCTGGTTCTGACTCGAAACAAAACAGC
AACAAAAAGCTGGGAGAATTTTTGAATCTGTTAAAAGCAGTGGTCAAGAGGAAGTTGGAA
AGTTTCCCAAAAGACCGTTTAAAGACTTCGATTATAACTGGCCAAGAATTAATGAGAGAG
GGGCAAGGAAGTATTGAAATTAAGGATCCACCAACGGAGGCGCAACAACATTTGATTAGA
AGCCTAGCAAAAGTTTTATTACACCAGTTTTCAAGCATAAATGGCAAAGTTAACACAGTA
AATGAAGGACAAGATAATTTGTTTCTATCCTTATTCGTTAAAAAAATTTCTATAGAGCAA
CAGTCCACATCACACGTCTCTATTAAATTGAACTTTCATGAGAAAATAAATTTGGGTCAG
CACATAGATTCTATTTTAGATTCAGAGGAGACCAACGAGTCGGACACTTATCACATGGGA
TCTGTTGACGAGTTCATTATATATCCCTTTTGCTGTCTGGAAGAGCAAGATGAGCTGAAA
AATGGCAGCATACTGTCCACAGAGTTCGACAAGATTGACTTAGAACTAGACGAGGATGAT
GGTTTTGAGGGAGAAACTTTAAACAATTGTATCAATTCGGTGGGAAATTTTGACATTCCA
CTAAGTAAGCAAACACTAAACTTAGTAAATATATCATATCTTCCAGGCACAACTTTCGAG
GGCCAATGGGAATCGTTGTATTTTGGTAACAATATTAAAGAAAGGTTATATAGCTACGCA
ACTATATCTCTCAAGATAGCAAGATTCAAACAAACTGGAGACTCCAATCAAGAAGACATT
ACAACGCTAATCACAAATAATAAATTACTCCTTGTCCATGGTCCTCCGGGAACAGGTAAA
ACAACGTTATGCAAAGCACTTTGCCAAAAATTATCTGTGAGGCGGGAATTTTCAGACGGT
TCCGATACCATTGATACTAATTATAAGGGGATAATAATAGAATTGTCTTGTGCACGCATC
TTTTCTAAATGGTTTGGAGAATCGTCAAAAAATATATCAATAGTATTCAAAGACATTGAG
GAGCTTTTAAAGGTCAATGAGGGACGAGGGATCTTTATATGCCTTTTGATAGATGAGGTT
GAAGCAATAGCAAGTTCAAGAACAAATTTGTCAAGTAGAAATGAGTCAACAGATGGAATC
CGAGTTGTGAACACTTTACTTACGCAACTTGACAGGCTGAAAAAATACCATAACTTTTTA
GCATTAGCCACGTCTAATTTATTAGATTCATTAGATGATGCTTTTGTTGATCGAGCAGAT
GGAGTTTTTTATGTTGGAAATCCAACAGCTGAGGGCATCCTCCACATTCTAAAGGTTTGC
ATAGAGGAGATGATAACTTCAGGTATAATTCTTTTTCACGCAAGATCAACTGGAGTCAAG
TTCTTCAATAAATATCAGGACATTTTGCGGAAAATTGCTATCAAATGCTCGACCGTTGAT
ATCAGTGGTAGAACAATAAGGAAATTGCCCTTGATGTGTCTGTCTGAATACTTCCGGACA
TTTCCTGTAGACGACGATGAGTTTGTTCTGGCATTAGCTATGTCAGCGCGGAAGCTGAGC
GCAGCGCGGAAGTGA
Promoter Sequence
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>PCH2 YBR186W
GACAAATTTTTATGAGCAAATGACGTGTTTACATTGATATACGTCTCTATGGCTTTGTTT
TTCCAGAGTAAAAAAGAAGGTTTAATGCCTGATTGAAAACGAAACAATGCGACTTGAACA
GAGTTCAAACCAAACGTGTAAAGTCTTCTGATCAATGCATTTGCAACAATGAGAGGATGA
GCAAATACATTTGGAAGGTTCTTGTAAGCCGAGGGGATAAATATTTCGGCAGCAACACCC
AGGTGCCGAGGATTAAAATCTTGCTGCTTACTTTTATCTTTCTTCTTTGTAGTTTCACTT
TCTTTATTCAAAATTAACCTCGAAGTTGAAAATAATCGCCGCTTGTTAAATGATATCAAC
AAGGATCTTGGAGGGAAGAAAAGGCATGTAGATCTTAATACACTCATCTCATAAGCTTAG
CTGAATGGATAGGCTTGCTTTCTGATGGAAATTTGCCTTGCTTTTCCAACTATTCCATTA
CTCAGGTTTTATTTTTTTATTTTGTAATATGGGGAGAAGGCCGGCAGAATATTTACGGAC
AAATGAATAAATTGGATTGGATTGACTAGTGGAACGTGTAAAGATCGCGATACTCCGTAC
CAATCACCGAAAGATTGCCCGTAACCGAAATGACTCCATTCTCTGAATTTTTTGTGAAAC
CAATATCTGAGACTCTTCCTTCATCTTATCAACGTATTGTTCAGTCAATTAAGTAAGAAG
TATATTTGAGCGCAGCCTTAATCATATATAGCACCAGTTATATGTTTGCCCCTCTCTTGA
GTTGAAAAACACATAATACATAGTACTGTACTTTTCTCTTTTTCATCGTTGGCGAAAATA
TAATCTTTCTCAAAAATATATATATATGTATATATATCCTTAGATTTGCCGTTGACAATA
AGGTGGGCGGCAAATCTACGAAATGCGAGGCGGTTAAAAGAGAGTGACAACATTTTCATA
AAAATATTCTGATCTCAAACTGAAGACATAAAATAAGGAT
Chr coordinates
Chr II from 600553-602103,602217-602360