Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
PYC2
Systematic Name
YBR218C
Strain
S288c
Description
Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PYC2 YBR218C
ATGAGCAGTAGCAAGAAATTGGCCGGTCTTAGGGACAATTTCAGTTTGCTCGGCGAAAAG
AATAAGATCTTGGTCGCCAATAGAGGTGAAATTCCGATTAGAATTTTTAGATCTGCTCAT
GAGCTGTCTATGAGAACCATCGCCATATACTCCCATGAGGACCGTCTTTCAATGCACAGG
TTGAAGGCGGACGAAGCGTATGTTATCGGGGAGGAGGGCCAGTATACACCTGTGGGTGCT
TACTTGGCAATGGACGAGATCATCGAAATTGCAAAGAAGCATAAGGTGGATTTCATCCAT
CCAGGTTATGGGTTCTTGTCTGAAAATTCGGAATTTGCCGACAAAGTAGTGAAGGCCGGT
ATCACTTGGATCGGCCCTCCAGCTGAAGTTATTGACTCTGTGGGTGACAAAGTCTCTGCC
AGACACTTGGCAGCAAGAGCTAACGTTCCTACCGTTCCCGGTACTCCAGGACCTATCGAA
ACTGTGCAAGAGGCACTTGACTTCGTTAATGAATACGGCTACCCGGTGATCATTAAGGCC
GCCTTTGGTGGTGGTGGTAGAGGTATGAGAGTCGTTAGAGAAGGTGACGACGTGGCAGAT
GCCTTTCAACGTGCTACCTCCGAAGCCCGTACTGCCTTCGGTAATGGTACCTGCTTTGTG
GAAAGATTCTTGGACAAGCCAAAGCATATTGAAGTTCAATTGTTGGCTGATAACCACGGA
AACGTGGTTCATCTTTTCGAAAGAGACTGTTCTGTGCAAAGAAGACACCAAAAAGTTGTC
GAAGTCGCTCCAGCAAAGACTTTGCCCCGTGAAGTTCGTGACGCTATTTTGACAGATGCT
GTTAAATTAGCTAAGGTATGTGGTTACAGAAACGCAGGTACCGCCGAATTCTTGGTTGAC
AACCAAAACAGACACTATTTCATTGAAATTAATCCAAGAATTCAAGTGGAGCATACCATC
ACTGAAGAAATCACCGGTATTGACATTGTTTCTGCCCAAATCCAGATTGCCGCAGGTGCC
ACTTTGACTCAACTAGGTCTATTACAGGATAAAATCACCACCCGTGGGTTTTCCATCCAA
TGTCGTATTACCACTGAAGATCCCTCTAAGAATTTCCAACCGGATACCGGTCGCCTGGAG
GTCTATCGTTCTGCCGGTGGTAATGGTGTGAGATTGGACGGTGGTAACGCTTATGCAGGT
GCTACTATCTCGCCTCACTACGACTCAATGCTGGTCAAATGTTCATGCTCTGGTTCTACT
TATGAAATCGTCCGTAGGAAGATGATTCGTGCCCTGATCGAATTCAGAATCAGAGGTGTT
AAGACCAACATTCCCTTCCTATTGACTCTTTTGACCAATCCAGTTTTTATTGAGGGTACA
TACTGGACGACTTTTATTGACGACACCCCACAACTGTTCCAAATGGTATCGTCACAAAAC
AGAGCGCAAAAACTGTTACACTATTTGGCAGACTTGGCAGTTAACGGTTCTTCTATTAAG
GGTCAAATTGGCTTGCCAAAACTAAAATCAAATCCAAGTGTCCCCCATTTGCACGATGCT
CAGGGCAATGTCATCAACGTTACAAAGTCTGCACCACCATCCGGATGGAGACAAGTGCTA
CTGGAAAAGGGACCATCTGAATTTGCCAAGCAAGTCAGACAGTTCAATGGTACTCTACTG
ATGGACACCACCTGGAGAGACGCTCATCAATCTCTACTTGCAACAAGAGTCAGAACCCAC
GATTTGGCTACAATCGCTCCAACAACCGCACATGCCCTTGCAGGTGCTTTCGCTTTAGAA
TGTTGGGGTGGTGCTACATTCGACGTTGCAATGAGATTCTTGCATGAGGATCCATGGGAA
CGTCTGAGAAAATTAAGATCTCTGGTGCCTAATATTCCATTCCAAATGTTATTACGTGGT
GCCAACGGTGTGGCTTACTCTTCATTACCTGACAATGCTATTGACCATTTTGTCAAGCAA
GCCAAGGATAATGGTGTTGATATATTTAGAGTTTTTGATGCCTTGAATGATTTAGAACAA
TTAAAAGTTGGTGTGAATGCTGTCAAGAAGGCCGGTGGTGTTGTCGAAGCTACTGTTTGT
TACTCTGGTGACATGCTTCAGCCAGGTAAGAAATACAACTTAGACTACTACCTAGAAGTT
GTTGAAAAAATAGTTCAAATGGGTACACATATCTTGGGTATTAAGGATATGGCAGGTACT
ATGAAACCGGCCGCTGCCAAATTATTAATTGGCTCCCTAAGAACCAGATATCCGGATTTA
CCAATTCATGTTCACAGTCATGACTCCGCAGGTACTGCTGTTGCGTCTATGACTGCATGT
GCCCTAGCAGGTGCTGATGTTGTCGATGTAGCTATCAATTCAATGTCGGGCTTAACTTCC
CAACCATCAATTAATGCACTGTTGGCTTCATTAGAAGGTAACATTGATACTGGGATTAAC
GTTGAGCATGTTCGTGAATTAGATGCATACTGGGCCGAAATGAGACTGTTGTATTCTTGT
TTCGAGGCCGACTTGAAGGGACCAGATCCAGAAGTTTACCAACATGAAATCCCAGGTGGT
CAATTGACTAACTTGTTATTCCAAGCTCAACAACTGGGTCTTGGTGAACAATGGGCTGAA
ACTAAAAGAGCTTACAGAGAAGCCAATTACCTACTGGGAGATATTGTTAAAGTTACCCCA
ACTTCTAAGGTTGTCGGTGATTTAGCTCAATTCATGGTTTCTAACAAACTGACTTCCGAC
GATATTAGACGTTTAGCTAATTCTTTGGACTTTCCTGACTCTGTTATGGACTTTTTTGAA
GGTTTAATTGGTCAACCATACGGTGGGTTCCCAGAACCATTAAGATCTGATGTATTGAGA
AACAAGAGAAGAAAGTTGACGTGCCGTCCAGGTTTAGAATTAGAACCATTTGATCTCGAA
AAAATTAGAGAAGACTTGCAGAACAGATTCGGTGATATTGATGAATGCGATGTTGCTTCT
TACAATATGTATCCAAGGGTCTATGAAGATTTCCAAAAGATCAGAGAAACATACGGTGAT
TTATCAGTTCTACCAACCAAAAATTTCCTAGCACCAGCAGAACCTGATGAAGAAATCGAA
GTCACCATCGAACAAGGTAAGACTTTGATTATCAAATTGCAAGCTGTTGGTGACTTAAAT
AAGAAAACTGGGCAAAGAGAAGTGTATTTTGAATTGAACGGTGAATTAAGAAAGATCAGA
GTTGCAGACAAGTCACAAAACATACAATCTGTTGCTAAACCAAAGGCTGATGTCCACGAT
ACTCACCAAATCGGTGCACCAATGGCTGGTGTTATCATAGAAGTTAAAGTACATAAAGGG
TCTTTGGTGAAAAAGGGCGAATCGATTGCTGTTTTGAGTGCCATGAAAATGGAAATGGTT
GTCTCTTCACCAGCAGATGGTCAAGTTAAAGACGTTTTCATTAAGGATGGTGAAAGTGTT
GACGCATCAGATTTGTTGGTTGTCCTAGAAGAAGAAACCCTACCCCCATCCCAAAAAAAG
TAA
Promoter Sequence
Download FASTA
>PYC2 YBR218C
ATTATGTCCATGATCAACTACTTCACCGTGTATCAGTGCACTATTCCTGGCACAAATAAA
GTATACGTAACTCACGGCGGCAGCATGCAAGCGTGCACCGAGCTTTTGAATGGCACCGTG
ACCATCCTGCGTGACGGCTATTACATCACCAATCTCATATGTATTGTAGTCGGACTTTTC
CTATATTTTGGATATTTGAAAAGGAAAATCCTCCATTTACAAAGTCTGCCAATCAGTTCC
TGGAGATGTACGTAACGACCCCTCAAACAAGAATTGTACGACATTACGTTCAAGAAAATT
TTAACGAGTATCGTAATATTTACAAGATCTTTTTATGTACTACAGGAAGCAGAAACAAAA
TGAGTATCAATACCAGTGTAAATCTGTTAATGAGAATCATCACATTATCCCAGTTTTTTC
CATGCAAGGGAAAAATATACTATACGACATTTCTATACTTTAATTATCAATTAAGGTCAT
CTTTCTGTACGAAAACTAACCACGATTGTCACTAACGACGTGTCCCTTACCCGACGCAGC
TGCTGATAGCGTACCGCACAGGCACAGCCAGCTCTTCTGTGATTGGCAGAGAGGGGTCCT
TCCTGCGGAAGACGCCGCAAAGGCACATATGACTAACCTTTTTTTTTTCGCAATTAATTT
TCTAATAGTTTTTCATTTTTTTTTTACAATTTTGGCAGTTACGTCTCGAGCTATTTATTA
TAAGAGTCAGAATTGGCGCAGGGAGTGTTAAGTAAGAAGTACTCCCCATCGGATATTTCC
TATTGTGTTTCTGTGATTTTTAGTCCTTTTTTCTTTTCTCTTACTTTCGGTATCCTTACT
TGATTACATACATAAACAAGCCCCTCTTTTCTTCCAAACTCTTGTAGCTTACTATCTGTG
GCCCGTCATTTGAGTTTGATTTTTTTGCCAATTACTATATTGCAAAATAAAGGACAGTTA
CTAGGAGAGAAAATAAGGGACATAGAGAACAAAATAAAAT
Chr coordinates
Chr II from 662249-658707