Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RRT2 Systematic Name
YBR246W Alias
DPH7, ERE1 Strain
S288c Description
Methylesterase performing penultimate step of diphthamide biosynthesis; hydrolyzes methylated diphthine to produce diphthine and allows Dph6-catalyzed amidation reaction to occur; deletion leads to resistance to sordarin and accumulation of methylatediphthine; WD40 domain-containing protein; involved in endosomal recycling; forms complex with Rtt10p that functions in retromer-mediated pathway for recycling internalized cell-surface proteins External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>RRT2 YBR246W
TAATCTTCTTAAGGGGCGACTTTTCTCTTATAATAATTTCATAAGAAGCAATCACAACAT
CAAAGTCACAACCTAAAAGTTTTTTTTGGATCAGTTCAGCTCTTTCTTCTTTATCTCCTT
GCAAAATAAAGGCGTTTACGTCTGGCGTCCATCTATTTATTTCTCTCAGCCAATTATTTA
AGGTAGACTTAGGCGCAATGACTAAAAATGGACCTGGAATTTTTTCAATGTACCTAAGAT
ATCCCAGAAATGAAATAGTTTGCAGGGTCTTACCTAAACCCATTTCATCAGCAAGGATAC
CCGCTATTTTGTTCTTATGCAGAGACACCAACCAGTTGACACCTTGGATTTGATAAGGTC
TCAATTGACCATTAACGTAAGCAGGTGATTCTCTGAATTGGAATTCAATGCTCTCATCAT
CATCCGAGTCTTCTTCTTTCAATAATTCCGCATCTTCTTCGTGTTCAGTCTTTCGTCTAC
GAACATCTTGGTGTTTGCCTTTGCCTTTGCCATTTGCTTTATTTTCTTCTAATACATCTA
AGACCTGCCTGAATTTGGGATCTTTAGCGGCTTTACTTTCAATAAAATGCTTGAATAAAC
CACTCAAGGATAGCAGATGTTCAAATCTTTTTGTAGTGCCTTCCAGATCAAACTTTTTAC
CATTAGCATCCTTCAGCAGGTAACGTTTTTTATTCGATTCAGGATCATGTGGAGGGAGAC
CGACCTGGAACGGTTTTAAATTCTCCAAGTACTCTTCTGAAGCAGTCATAATTGAACCAG
ATGAAATACAATCGTATTTTTTTTTTTCTTGCAAAAATATGGCGAGAATAATTTTGAATA
GGTTCTCATCTTTGTCCTTTTCATTGCAAGAATTGTTTTCGTGTTTTTTTCTCATTCTAG
TATAGAACTTGAAAAAGTGAAAATTTGCAATAGCTAACATATAGGCCATAATAGGGTATT
TCTACATCCACCTCTAGCTGGTTTTTGCATAGCTATACAT
Chr coordinates
Chr II from 711591-712754
