Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TYC1 Systematic Name
YBR296C-A Strain
S288c Description
Inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C); binds to APC/C and inhibits the activity of both APC/C(Cdc20) and APC/C(Cdh1); inhibits the binding of Cdc20 and Cdh1 to APC/C; overexpression results in increased sensitivity to microtubule poison; originally identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; functional homolog of human MAD2L1BP (p31comet) External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TYC1 YBR296C-A
ATGAAAGTGCTAGATGATTGGTTTTCAAGGAAGTTCTCAAAAGCTGTACACGGAAACAAT
CACGGCACCATTTCCTTGTCAACTCTGTCTTATATCAGAGTCCATAAACTAGTAAAATGA Promoter Sequence
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>TYC1 YBR296C-A
GGAATAGTATCTTTCCGTCAAGAGAAGCAAATAATACACCTTGCGTAAAAGCTGTTGCTC
ACGAAATGATAGTGATTCGTATGCTTTTTCACGATGTAACCCTGCTACAATAACAAGGCC
AATAGCTTCACGACAAAGTCTGTATGAATTTCTTACATCAGAAGACTGTGAAAAACAACG
TAGCAAGCAATAATATGTCATAATTCGGAAAATGTCTCTGCCGCTAAGGTCATCAAATTG
TTGGCGTGAGGACATACAGAGAACGGCTAATTGTTTTCCAGTAAACGAAAATCCCCCCTC
AGATTCTAATTCGCTTTGTAGATCGCTAAGATTGGCTGCTGAAAGAGCTACGAGAAACCA
ATAAACGTAATGGTCATTGTATTCTTCGTCCAAAAGCTTGTGAAGGTCATCATAAGAGAG
TAAAGGCCAGATAACATATAGATTGTCGTGATAAAGCCTCAAACACTGATCAATCACCTT
TTTAGGAACCTTCATTAATATTTCTGCCGCTGCCGTACAACTTTTATTATCTATAAACAT
TTTGGCCTTTGGTATATACTTTAAGCTTCTAGTTCCAATAGGCTTTGAGCCTCTTTTTTT
TAATGGTTGCTGATATGTGCAATCGAAATTGTGCTCAATACAGCGACTACATGGTTTTTT
ACCATCACACTTTACTCGACGGACACGACAATAGTCGCATGCATACTTGACTAAAGTCAT
ATTTAGAACATAAATATCTTCAAGATGCTCTCGTTCGATGTTTGATATTCAATATTTACA
CTCTAGTGTTTTCCCGAGAAAGAAACCTTCTGAAATGATTTTTTGTTCCTTTTTAATCTA
TTGAAAAATGGCGGTACGGACAATAAAATCCGGGGGCGGGGTAAATTGCGCATGGCCGTG
GAATGTCACTGCAAAGTGAACGAGAAGATTAGAACACGGAATAAGGAAAACTTCTGGGGA
ATTTATTTTTCAAGATTTGGTTCCAGGTTTTTCCCCAGAA
Chr coordinates
Chr II from 800242-800123
