Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MRC1 Systematic Name
YCL061C Alias
YCL060C Strain
S288c Description
S-phase checkpoint protein required for DNA replication; couples DNA helicase and polymerase; stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; defines a novel S-phase checkpoint with Hog1p that coordinates DNA replication and transcription upon osmostress; protects uncapped telomeres; Dia2p-dependent degradation mediates checkpoint recovery; exposure to ethanol affects localization; mammalian claspin homolog External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>MRC1 YCL061C
ATGGATGATGCCTTGCATGCTTTGTCCTCGTTGACTGCAAAGAAGAGAACTACCACCTAC
AAAAAAGTTGCTGTTCCCATACTAGATGAGAACGATAATACTAATGGAAATGGGCCCAAT
GACATAGACAATCCGCCAGAGTTGACTGGGAACGGGTTTTTATTTGCCAATGCCACATTA
AATCGTGTTAAGAACAGATTAGAAGGCAAGAAAGCACCCGAACAGAATCACAATAATGGA
AAAGATAGGAGTGAGAATTCGTTACCAACTCAATTAATCTCTAATCTTTACGATGGTGGT
GAAGAGCTGGAGAAATCCGAAGTTAAAGATAATAGTTACAGTGAGAAAAATGTCTCTTCT
TCATTCACGCAGACGCAAAGAATACCTGTCAGCATCCAACAAGACAAGGTGTTTAACGTA
CCTATCCATTCCGTTAATGACGGGAAACCCACCCAATTAATCAAAGAAGATGGTCTCGTC
AACGAAACTTCTCAAGCGCTGAAAACACCTCTCACGACAGGACGGCCAGGGGCTACACAG
CGTATAGATAGCAGCGGTGCAACCTCACAAACTCAGCCTATAAAATCAATTGAACCACAA
TCCCAAATAATTACGACTTCCAGCAATCATTCTAATGCTCTGTCGCCGAAAATTCCTATA
ATTCCAACGGAACTTATTGGAACTAGTCCTTTATTTCAGTCCATTCAAAATCGTGGTCCT
GACACCCAAATGGATGTACCACCACAGACTGCGCATGATGAGGATAAGACACAAGCAATT
GGTATTCCACAGGCTACGCATCAGGAACAGAAAACCCAAATAGATACAGTCGCACAAACA
CTTCAAGATGAAGTACCACACACATTAAAAATTCGGGAAATACAAAGCGAATTGGCTTCA
GAAGATTCTAAAAGGGAAAAAGCTAGAAATGTCGAATACAAAAAACCGCAAAAGCCAATA
CCAACCAAAAAATTTTTTTCTAAAGAGTCTTTTCTTGCTGATTTTGACGATTCGTCCTCA
AATGAGGACGATGATATAAAGCTGGAAAATGCACATCCAAAACCAGTACAGAATGACGAT
GAACTGCATGAGAACAAAAGTGTTGAATTAAATCTAACTGATGAGACAAGAATAAATGAG
AAAAGGGTTCCACTATTGAGCTCCTATGCTAATAATTTGAAACGGGAAATTGACTCCTCG
AAATGCATAACACTGGACCTCGACAGCGACAGTGACGAATATGGAGATGATGATATGGAT
AGCATTAAATTATCCAAAGATGAAAGCGTTTTGCCAATCTCTCAGTTATCAAAGGCGACT
ATATTAAACCTGAAGGCAAGACTCTCTAAACAAAATCAAAAGTTGTCTCAAAGGCCGAAT
AAAAGTAAAGACCCAAAAGTTGATCATAATGTACTATTAAATACCTTAAGGAAAGCTAGC
AGGAAACAAATTCTGGATCATCAGAAAGAAGTGATTGAAACGAAAGGTCTGAAGCTGGAG
GATATGGCCAAAGAAAAGGAAATAGTAGAGAACTTGCTAGAACAAGAAATTCTTAGAAAT
AAAAGAATCAGACAAAAAGAGAAGAGAAGGGAAAAACTTGAAGAAAATGACTTTCAATTG
AACGCCCATGATTCCGGTTCTGACTCAGGGTCAGAGTCTTCTGGATTTGCATTGAGTGGT
AATGAAATTGCCGATTATGAATCATCTGGTAGTGAAAATGACAATCGTAGAGAATCCGAT
AGTGAAAAGGAAGATGATGAAATTATTCTAAAGCAAAAAAAATCCCACCACGTGAAACAT
ATCATTAACGAATCAGACTCTGATACCGAAGTCGAAGCCAAACCCAAAGAGAAAGCTGAT
GAAAGTCTACCGAAAAGGATCGCCATTAATCTGGGCCATTACGGTGATAATATCGGAGAG
GATACCGACAAATTTCAAGAAACCAATGTTCTAGATACACAAAACATTGAAGAGGTGATG
GCCGAAAGAAATACAATCGAAAATGAAGTCAAAGATGATGTATACGTCAATGAAGAAGCT
GATGAAGCAATTCGCCGTCAGCTGATTGACAAAGAGAAATTGCAACTAAAACAGAAAGAA
AAGGAGCACGAGGCTAAGATAAAAGAGTTGAAGAAAAGAGGTGTCACAAACTTCTTTGAA
ATGGAAGCCGAAGAATCCGAGGATGAATGGCATGGTATCGGTGGTGCAGATGGAGAAGGA
TCTGACGACTATGATTCTGACCTAGAAAAAATGATCGATGATTATTCCAAGAACAATTTC
AATCCTCATGAAATCAGAGAAATGCTTGCCGCAGAAAATAAGGAAATGGATATCAAAATG
ATAAACAAAATTCTTTATGACATTAAAAATGGAGGATTTCGTAATAAAAGAGCAAAAAAT
AGCTTAGAGCTAGAACTAAGTGATGATGATGAAGACGACGTACTACAACAATATCGTCTC
AAAAGGAGAGAATTGATGAGAAAAAGGAGATTAGAAATTGGCGATGATGCAAAGCTTGTT
AAAAACCCAAAGTCGAGCGCATTTTTTGAAAGTATGGTGGAAGATATTATCGAATATAAA
AACCCCTTCGGGGCTGAAGAGGAATATAACCTAGACATTACAAGTACGGCTACTGACCTA
GATACTCAGGACAATAGCATTAATGTAGGTGATAATACGGGAAATAATGAACAGAAACCT
GTAGATCAAAAGAACAAAAAGGTTATCATATCTGAAGACTTTGTGCAGAAAAGCTTATCC
TTCCTAAAAAGTAATAATTATGAGGATTTTGAAACGGATAAGGAGCTATCAAGGATACAA
CATGGCAATGATGAAGCAATTGAAGATTTATATACCCTAAAACAGAATAGTTCGATAAAG
TCATTCACAAATTCTCAAACTGATTCGACCACTTCAAAAACAGTAAACACAATAATTGAC
TTAGAAAAGCGCCCAGAGGATGAAGATGAGGTGGAAAATGGAGATACATCACTAGTTGGC
GTTTTCAAACATCCATCAATAATCAAATCCTTTGCGTCCAGAACAGACATAAATGATAAG
TTTAAAGAAGGTAACAAGACAGTCAAGATTCTAAAGTCTTACAAGACAGTGGGGAGTTCA
AAAGCTTCTATCACATATATGGGGAAAACGAGAAAATTAATAGCACCAAAGAGGAAAACT
GAAGGGAGCCACCGCTACCACCATGACCATCATAATAAAAAAATGAAAATGAAAACGAAA
ACAAAATCGAATAAACTTTTTGAAAGCGGACAAGATAGCTTTGATAATTAG Promoter Sequence
Download FASTA
>MRC1 YCL061C
GCTATCATTTTGAAAGCCAGAGATTTGATCAAATTATTGGCGAGATCCGTTCCTTTCCCG
CAAGCCGTTAAGATCCTACAAGATGACATGGCATGCGACGTTATTAAAATTGGTAATTTC
GTTACTAACAAAGAAAGGTTTGTCAAGAGAAGACAACGTCTTGTAGGCCCTAACGGTAAT
ACTTTAAAGGCTTTGGAACTTCTAACTAAATGTTACATTCTAGTACAAGGTAACACAGTA
AGTGCCATGGGTCCCTTCAAGGGCTTGAAGGAGGTCCGTCGAGTAGTAGAAGATTGTATG
AAAAATATTCACCCTATCTATCATATCAAGGAATTAATGATAAAAAGAGAATTGGCAAAA
AGGCCAGAGTTAGCCAATGAAGATTGGTCAAGATTCTTGCCCATGTTTAAGAAGAGGAAT
GTGGCCAGAAAGAAACCCAAGAAGATCAGAAACGTCGAAAAGAAGGTCTATACTCCATTT
CCTCCTGCCCAATTGCCTAGAAAGGTTGATTTGGAAATTGAAAGTGGTGAGTATTTCTTA
AGCAAGAGAGAAAAGCAAATGAAGAAATTAAATGAGCAAAAGGAAAAGCAAATGGAAAGA
GAAATCGAAAGGCAGGAAGAGAGAGCAAAAGATTTCATAGCTCCGGAAGAAGAAGCATAC
AAGCCAAACCAAAATTAGTTTACACCGCTACGGAATCCTTCATATATGTCTATATATATA
TAGAAACACACACACATTTCGTTTACTTAGATATGTTTGTAAAGTGAAAGAAATTCTTAC
TAGGACACCAACTCTACTGGCTCTCATATGCAGAGAGATATACATCAATACTTGAAATTT
TCCTTATCCTTCTTCGACGCGTCATGAAGAGATAGAATGCGTAAAACGCGTTTGCTTCAA
TAGCATTTCAAACACATTATGTTGGAAAAAAACCAAGAACAGACAAACAACTAAGGAAGT
TCGTTATTCGCTTTTGAACTTATCACCAAATATTTTAGTG
Chr coordinates
Chr III from 22106-18816
