Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
CIT2 Systematic Name
YCR005C Strain
S288c Description
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle; catalyzes condensation of acetyl coenzyme A and oxaloacetate to form citrate; expression is controlled by Rtg1p and Rtg2p transcription factors; SCF-Ucc1 regulates level of Cit2p to maintain citrate homeostasis; oxaloacetate-dependent positive feedback loop inhibits Cit2p ubiquitination; CIT2 has a paralog, CIT1, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CIT2 YCR005C
ATGACAGTTCCTTATCTAAATTCAAACAGAAATGTTGCATCATATTTACAATCAAATTCA
AGCCAAGAAAAGACTCTAAAAGAGAGATTTAGCGAAATCTACCCCATCCATGCTCAAGAT
GTAAGGCAATTCGTTAAAGAGCATGGCAAAACTAAAATTAGCGATGTTCTATTAGAACAG
GTATATGGTGGTATGAGAGGTATTCCAGGGAGCGTATGGGAAGGTTCCGTTTTGGACCCA
GAAGACGGTATTCGTTTCAGAGGTCGTACGATCGCCGACATTCAAAAGGACCTGCCCAAG
GCAAAAGGAAGCTCACAACCACTACCAGAAGCTCTCTTTTGGTTATTGCTAACTGGCGAG
GTTCCAACTCAAGCGCAAGTTGAAAACTTATCAGCTGATCTAATGTCAAGATCGGAACTA
CCTAGTCATGTCGTTCAACTTTTGGATAATTTACCAAAGGACTTACACCCAATGGCTCAA
TTCTCTATTGCTGTAACTGCCTTGGAAAGCGAGTCAAAGTTTGCTAAGGCTTATGCTCAA
GGAATTTCCAAGCAAGATTATTGGAGTTATACTTTTGAAGATTCACTAGACTTGCTGGGT
AAATTGCCAGTTATTGCAGCTAAAATTTATCGTAATGTATTCAAAGATGGCAAAATGGGT
GAAGTGGACCCAAATGCCGATTATGCTAAAAATCTGGTCAACTTGATTGGTTCTAAGGAT
GAAGATTTCGTGGACTTGATGAGACTTTATTTAACCATTCATTCGGATCACGAAGGTGGT
AATGTATCTGCACATACATCCCATCTTGTGGGCTCAGCACTATCATCACCTTATCTGTCC
CTTGCATCAGGTTTGAACGGGTTGGCTGGCCCACTTCATGGGCGTGCTAATCAAGAAGTA
CTAGAATGGTTATTTGCACTTAAAGAAGAGGTAAATGATGACTACTCTAAAGATACGATC
GAAAAATATTTATGGGATACTCTAAACTCAGGAAGAGTCATTCCCGGTTATGGTCATGCT
GTGCTAAGGAAAACTGATCCTCGTTATATGGCTCAGCGTAAGTTTGCCATGGACCATTTT
CCAGATTATGAATTATTCAAGTTAGTTTCATCAATATACGAGGTAGCACCTGGCGTATTG
ACTGAACATGGTAAAACCAAAAATCCATGGCCAAATGTAGATGCTCACTCTGGTGTCTTA
TTACAATATTATGGACTAAAAGAATCTTCTTTCTATACCGTTTTATTTGGCGTTTCAAGG
GCATTTGGTATTCTTGCTCAATTGATCACTGATAGGGCCATCGGTGCTTCCATTGAAAGG
CCAAAGTCCTATTCTACTGAGAAATACAAGGAATTGGTCAAAAACATTGAAAGCAAACTA
TAG Promoter Sequence
Download FASTA
>CIT2 YCR005C
GACCAATGTTAATGAAAACTTGAACTGCTGAAGTGTGATATTCAATGTATGAGATAATCC
ATTAAATCATCTACAGTTTAAAGACTGTAGGCTTACATGACCGTTTATCACTGCGATATT
GGAGGAAGCGCTTCGGATCAATGGACCTTTTACTTAGCAGAGCGAAGGCTGAAAATCATG
AACCCCAACAGCATGTGTGACCTCTCTTCTCACGCCTGGCAAGAAACCAAACTACGGCAT
ACATTCAGCGCACCAAAAAGGAACTCCGTACTATTTACATTAAAAACAAGAAAATGTGTT
GCCATTTCCGTAAAATGAATGGCCCATGTTCATACGCGTATGCAACCGTCTTATTTACAC
TCCGACTAATGTCCTTCTAATTACTGTGGAAGACGGCCGTATAAGCGTCCTTCTGTGGTT
TAGATATGCTATACCGGCGGAACTTTGTTACACACGGCTCGCGCGAATCCTTAGGGGAAA
ACATTGCGCTGACTTTCCCCAGAGTTGTTGCCACAACATAAGCCGCTTTGGAGTGTTGAA
CAAATCCGTCCTTGGGTCATTCAATCAATGGCTTGGCGGTATCTCAAAAGAGCGCAAACT
AATAGCGCGCACATTCGACGCATTTATCCGGTGGTCATCGACTAGGGGCGAAGAGGTCAC
GACCTATTTTTTCTTGCAGAAAAAAAGTGTGACCTTTTCCGTAGCTAGACGTCTATCAGG
GCGTCAGCAATGGGAGGCACAGCGGAAAAACAATAACAATGGTAAGCGCAATTACCTTTT
GAGCGTTACATTCGTATGAAATTGGTGACGTTAATCTAAAGATAGTCATGCTCTCAAAAG
GGCCCATTATTCTCGACGTTGAGCGTATATAAGACTATTAAAACTTGGTTCTTTAGATAT
GGTGTTCGTTCCTCATTATTAAGTTTCAGGGAACAATATCAACACATATCATAACAGGTT
CTCAAAACTTTTTGTTTTAATAATACTAGTAACAAGAAAA
Chr coordinates
Chr III from 122328-120946
