Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
HCM1
Systematic Name
YCR065W
Strain
S288c
Description
Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources, NAD synthesis, oxidative stress resistance; regulated by cell wall integrity checkpoint; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HCM1 YCR065W
ATGATGAATGAAGACATATCCATCATTGATGGCCATAATAGTTTTTTAACGGAAAAAAGC
ACCGTGCTATTAACCCAAGCCAAGAGAACACTAGAAGACGAAAAGGAAATGATTACTCCC
CCGAGCTCAACTGTGAGAAAAACAATGAAGGAAGTAAATAAGAGGCCGTCGCATCCCCTC
TCACCGGATCACTCGTCCCCAATTGCTCCATCTAAGGCCAAGCGCCAAAGATCGGACACA
TGCGCTCGGTCCAATGGTAACCTAACCTTGGAAGAAATTCTTCAATCTTTGGAAAGAAGA
AGAATAAATGGTGAACTCGCCAAGAAACCTCCATATTCGTATGCAACTTTGATTTGCTTG
GCCATTTTGCAATCTCAGGAGGGAAAGCTAACGCTATCCCAGATATATCATTGGATCCAC
GTTCACTTCCCTTATTACAAGCAGAAAGATGCTAGTTGGCAAAATTCAATAAGACATAAC
TTGTCTTTAAATGATGCGTTCATCAAGACTGAAAAGTCCTGCGATGGTAAGGGTCATTTC
TGGGAGGTCAGACCGGGTGCCGAAACAAAATTTTTCAAAGGTGAAAATCGTGGTTATGAA
TTTGTAAAGGACTCCTTACAAGACATTGGGAAGTATTTTGAAATAGATTCTACACTTGAT
GAATTAGAACAAGTTGAGAGTGGAGAAGGCAATGATGATCTTCCTGACGAGGAAGAAAGA
GAGGAAGCAGGGAAATTCCCTTCCATTGAAATTCAATTGAACTCCTCCCCTATACTGAGA
GTTTCCCAGTTACATCACATACCGCAATTGAAAACAGACAACAGTGTACTGAACCCTCAC
GAAAACCTAGAATCGATGCGGAACATGATAGAAAACGATGTCAACAATATAGATTCCTTG
GAACCTCCTTATGTCATGAAGAAATATCATACTTCTTTAGGCTTACCGTCGCTGGTGAAT
GCCAAAGATCATTTCCAGGCGGGTGTGAAAAACAATAATATCACCCAGGCAAATAGATTT
AATACACTCCCTATAACTAGCGCAAAGTCTCCTCAGAATTTCAGAAAATATTTCACCTCA
TTCAATTCAAATTTTGAAGATTTATCTCCACTTCGAAGTAATGTAGGGGCTGGTTCTCTA
CTCGACCCACTTCCGTATTCCCCATTGAAGCTGTACGATCAGAAAAATCTTGCGCTCATG
TCGAAACCACAATCTCAGCAATCATATTCCAATTCTCAACTTCCACCTCCACCTTCCTCT
CATGGTTCGGACTTACTTAAAACACCCAAGATGAGGCATTCCGATGGCTTAGAGAAAACC
CCATCGCGGTTGATAAGCACACCTAAGGACGGTAACTCGATTTTGAGGAAATGGCAGACT
CCTTCACACCTTTTTGAAGATTTGTACTGTTCTCCGCTATTTAGAGCTATAGAGACTCCA
ATCAGGTATATCACGACGCCGGGGGGCACTTTGGAAACCCAAATTTCACCAAGAAAGTCC
TCTGCACCCGATGTCCTCACAAGCGCAACGAATTCCAAATTTGCTTCAAGCGGGCTGTTT
GGCGTGGATGTTTATTCTGTTTGGAAGCGCGCAACTGAAAAGATTTCTGATGGTAACAAT
ACTACGGATAGCAATCAAAAACATCATCCTTATCATAATCACCCTTCCAACGATAGCGGT
AATGAAAAGAATTGA
Promoter Sequence
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>HCM1 YCR065W
AAAACGACATGCCGCGCATAAAGACCAGAAGATCCAAGCCTGCACCTGACGGGTTCGAAA
AAATCAAGCCAACCCTCACAGATTTCGAAATCCAACTCAGAGATGCCCAAAAGGACAAGT
CGTCTAAGCTCGCAGCAAAGTCCAATGAGCAGCTCTGGGAGATAATGCAACTCCACCACC
AGCGCTCTAGATACATATATACTCTGTACTACAAGAGAAAGGCCATCTCCAAAGACCTTT
ACGATTGGTTGATAAAGGAAAAGTATGCTGATAAATTGCTAATTGCCAAATGGCGCAAAA
CCGGGTATGAAAAACTGTGCTGTCTGCGCTGCATTCAAAAGAACGAAACTAACAACGGTA
GCACTTGCATCTGCAGGGTGCCTCGTGCACAGTTAGAGGAAGAAGCACGCAAAAAGGGCA
CACAGGTGTCCTTCCATCAGTGCGTCCACTGCGGCTGCCGTGGATGTGCAAGCACAGACT
AACGACTATATGCACGTTGCAGTATTGTTCTGGCCATGTAATTATCTCTCTCCCAACGTT
TTAGAAGAGGTTTTCGTCTCCTTCGTCAAAGACGACCACTTTCCCATTTTGGTCATTGGA
ACGCGAAAAAACAAAACAGACGCGAGAACGCGACGCGAAAAAATATATTTTTCCGTTTTT
TTTTTTTTTCGGAACAAAGATAACGCGTTAAAACCTGTGGATGTAATAAGGATCTGAAAC
ACTGACTAAAACGCGTCCTCATTTAAAATCAAAAAATTACTTCTTCTCCTCCCTTACGGT
GCCCTTTGATCCTTCTCAAACTTTAAATATATGTTGCATGATTAATTGAAAATCATATAG
AGTATATCTTAACAGAGGTTCCAACGCTTTAAATCGTATTCTATTCTTTTCCCCCCTTTT
ATTATAGTTACATCTACTATTTGAGCTTCTTTTATTGACCGAAACTACCTCTTATTTCGA
AGCAAAAAAAAAAAAAATCAACAAAAATTCCAACTTTTCA
Chr coordinates
Chr III from 229310-231004