Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TSC13
Systematic Name YDL015C
Strain S288c
Description Enoyl reductase; catalyzes last step in each cycle of very long chain fatty acid elongation; localizes to ER, highly enriched in a structure marking nuclear-vacuolar junctions; coimmunoprecipitates with elongases Elo2p and Elo3p; protein increases in abundance and relative distribution to ER foci increases upon DNA replication stress; human homolog TECR implicated in nonsyndromic mental retardation, can complement yeast mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>TSC13 YDL015C
ATGCCTATCACCATAAAAAGCCGCTCTAAAGGGTTAAGGGACACTGAAATTGACTTATCC
AAAAAGCCTACTTTAGATGATGTTTTGAAAAAAATCTCTGCTAATAACCACAATATCAGC
AAGTACAGGATAAGATTAACCTACAAAAAGGAATCTAAACAAGTTCCGGTTATTTCAGAA
TCGTTTTTTCAAGAAGAGGCTGATGACTCAATGGAATTCTTCATCAAAGATTTGGGTCCC
CAAATTTCATGGAGATTAGTCTTCTTTTGTGAGTATTTGGGTCCAGTCTTGGTTCACTCC
CTTTTTTATTATCTATCTACCATTCCCACAGTTGTTGATAGATGGCACAGTGCTAGCTCC
GACTATAATCCATTTTTAAACAGGGTTGCATATTTTTTAATTTTAGGACATTATGGAAAG
AGATTATTTGAAACCTTATTTGTTCACCAATTCTCTTTAGCTACTATGCCAATTTTCAAC
CTGTTCAAAAATTGTTTCCATTACTGGGTTCTAAGCGGTCTCATTTCATTCGGTTACTTT
GGCTACGGCTTCCCCTTTGGGAATGCTAAGTTATTCAAATACTATTCATATTTGAAATTG
GATGACTTGAGTACATTAATTGGTCTTTTCGTGCTTTCAGAACTATGGAACTTTTATTGC
CACATTAAATTGCGCCTATGGGGTGACTATCAAAAGAAGCATGGTAACGCTAAGATCCGT
GTCCCATTGAATCAAGGTATTTTCAATCTTTTTGTTGCTCCCAACTATACTTTTGAAGTT
TGGTCTTGGATTTGGTTTACTTTTGTGTTCAAGTTCAATTTATTTGCCGTTTTATTTTTG
ACTGTTTCAACAGCTCAAATGTACGCATGGGCTCAAAAGAAAAACAAAAAGTATCATACC
AGAAGAGCATTCTTGATTCCATTTGTATTTTGA
Promoter Sequence
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>TSC13 YDL015C
CTGGACCAACAACATCTGAAACGTGAGAAACAGAAGTACCGGAAGCAGCACCTAAATATA
AAACTTTCTTGCCTGGGGCAATAAATAATTCATCTAGACCACCCATAATACCGGCAGCCA
ACTTAGATCTGAATGGGTTCCATACACGGTATTCGACCTTGGTTGGTGGGACACCATCTT
CCTTAGATGGTTCTTCAACGGAGATTCTCTTTTCACCATAAACTGATTCACCTGGGGCCA
TGTTCTTGGTAACTAGCAAATCTTCTTTACCTCTAGCAATGTAAACACCGGCATGTCTAT
GTGGTTCAATAACGACCTTGGCACCACCACGGGCACCACCAGCAGCGCCACCTCTACCAC
CTCTGGAGCCACCACGGGCACCACCACGAGAACCGCCTCTACCACCGAAGCCGCCTCTGG
AACCACCACGGGCACCACCACGAGAACCGCCTCTACCACCGAAGCCACCTCTGGAACCAC
CGCGAGCACCACCACGGGAACCGCCTCTACCACCGAAGCCACCTCTGGAACCTCCACGGG
AACCACCTCTGCTACCTGGTCTGAATGACATTACTGTTTTAGTTGATTTGAGTTAATTTG
ATCGGAGTTATTGAAAGCAATGGGCAACTTAGATTTATCCGATGAATGATATCTAATTGT
TTCTCGAAGAATAACTTATATAACAGTAGTATACCGATGTAAGGAAAACTTCTTGGCTAT
GTAAAACTTTTTGAAAGTTAGAGGAAGAAAGTATTATACATTCAAGAGAGATGAGCTTTC
CAATTTGAAAAATTTTTCAAGAAAAAGAAAAAATTTGAAAAAAAAAAAAGAAAAATATAA
TAAACATATCATTTTGTACGCAAAAAGTTAAGGAATTATGAAAAGGGACTAAGAGCGTGA
ATTTTACAGAACGGAGGACAGTAAGATTATATTCTATTTAGCTATCTAGAAACCAATTGA
GCTATTTGAGAGAGATACATATTTTGAATTTAATTTGAAA
Chr coordinates Chr IV from 426934-426002
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