S.cerevisiae - Yeastract

Locus Information

Standard Name	CDC7
Systematic Name	YDL017W
Alias	LSD6, SAS1
Strain	S288c
Description	Ser/Thr kinase and catalytic subunit of DDK (Dbf4-dependent kinase); required for origin firing and replication initiation; phosphorylates MCM subunits and Cdc45p to drive assembly of the pre-IC and the replicative CMG helicase (Cdc45-MCM-GINS); regulates pre-meiotic DNA replication, meiotic DSB formation, monopolar attachment of homologs during MI by recruiting monopolin to kinetochores, and regulation of middle meiotic genes including NDT80; complemented by co-expression of human CDC7 and DBF4
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>CDC7 YDL017W CAGATAGCATATTCTCCCTTATGTTGGCCTATAAATGACCATTCACCTTGACGTTCACCA GATCTCTCGATTATTGGCTTGTTTTTGTCATCAGGAGCAAATATTTCGTAGTTAACATCA AAGTCATTGCTCTCTCCTTGCTGTACTGCAAAATAATATGAGATTGTACAGTCAATTTCC GGAGTTAGCGTATATAAGCACTCCTTTCGACCTTTATTCAGTTCAAATGTCAACGGTGAT GCCTCAGCAAAAAATTGTGCTAAAAAAAAAAACTGGAAGAAAAGTACACATAAATTGGAC ATGACGGAGTTTTTTAGTCAGTTCACAGTGTCCCTTCAAGTACGGTAACTATCAAGAGCC TTACCAGTTTCTGTCAAGATATTGTCCCCCCAAATTCTTTCATTGAGGAGAGGATTATGA AGAACGCGTTCTGTTTTAAAGAGAGAAAAATTCAGGTCAGGACGCGTTGGTCTCACCTTT GTTGACATAATGACCATGACAGTGTAGGAAGTCTAAGTAGTATGTGGAAACCTACGCGAT CATACTGATACGTTCGTAAACTTTATCAACGAACGACGCTTTTTTTTTAAACCTCTATAT AAGCATGTTTTTAGCTTGGGAAATTAAGGTGTAGCCCTGGTTTTGAAGATAATTAAGAAT CTAATGGGGCAATGCTTGTGTAGATGACATTTTATAGAGTAAAATTACTTCCCGTTTAGC TCGATAAACGCCTTAGGCCTACATAAATCTTAAACATTTGTCCCCGGTCAGCTTTTAAAT TATGTCTTCTTTGCCCTGGGGCGTCTTCTTGAACGGCATCAATTTAGTGAGTAGAAGAGC ACTTCACATTTCCGCCTAAAATCAATGCAAGAACCATTAACAAAAAAAACCGCTCAGCAG GCGTAACGGGAAGTAACAGACTACCTTAAATTTTCAATAACAATTGTGCTATTATCTAAT TTTCTTAGGAAAGAGGCAGTTTCGAAGTAGAACAATCATA
Chr coordinates	Chr IV from 424209-425732