Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
GPD1
Systematic Name
YDL022W
Alias
DAR1, HOR1, OSG1, OSR5
Strain
S288c
Description
NAD-dependent glycerol-3-phosphate dehydrogenase; key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; protein abundance increases in response to DNA replication stress; constitutively inactivated via phosphorylation by the protein kinases Ypk1p and Ypk2p, dephosphorylation increases catalytic activity; forms a heterodimer with Pnc1p to facilitate its peroxisomal import
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>GPD1 YDL022W
ATGTCTGCTGCTGCTGATAGATTAAACTTAACTTCCGGCCACTTGAATGCTGGTAGAAAG
AGAAGTTCCTCTTCTGTTTCTTTGAAGGCTGCCGAAAAGCCTTTCAAGGTTACTGTGATT
GGATCTGGTAACTGGGGTACTACTATTGCCAAGGTGGTTGCCGAAAATTGTAAGGGATAC
CCAGAAGTTTTCGCTCCAATAGTACAAATGTGGGTGTTCGAAGAAGAGATCAATGGTGAA
AAATTGACTGAAATCATAAATACTAGACATCAAAACGTGAAATACTTGCCTGGCATCACT
CTACCCGACAATTTGGTTGCTAATCCAGACTTGATTGATTCAGTCAAGGATGTCGACATC
ATCGTTTTCAACATTCCACATCAATTTTTGCCCCGTATCTGTAGCCAATTGAAAGGTCAT
GTTGATTCACACGTCAGAGCTATCTCCTGTCTAAAGGGTTTTGAAGTTGGTGCTAAAGGT
GTCCAATTGCTATCCTCTTACATCACTGAGGAACTAGGTATTCAATGTGGTGCTCTATCT
GGTGCTAACATTGCCACCGAAGTCGCTCAAGAACACTGGTCTGAAACAACAGTTGCTTAC
CACATTCCAAAGGATTTCAGAGGCGAGGGCAAGGACGTCGACCATAAGGTTCTAAAGGCC
TTGTTCCACAGACCTTACTTCCACGTTAGTGTCATCGAAGATGTTGCTGGTATCTCCATC
TGTGGTGCTTTGAAGAACGTTGTTGCCTTAGGTTGTGGTTTCGTCGAAGGTCTAGGCTGG
GGTAACAACGCTTCTGCTGCCATCCAAAGAGTCGGTTTGGGTGAGATCATCAGATTCGGT
CAAATGTTTTTCCCAGAATCTAGAGAAGAAACATACTACCAAGAGTCTGCTGGTGTTGCT
GATTTGATCACCACCTGCGCTGGTGGTAGAAACGTCAAGGTTGCTAGGCTAATGGCTACT
TCTGGTAAGGACGCCTGGGAATGTGAAAAGGAGTTGTTGAATGGCCAATCCGCTCAAGGT
TTAATTACCTGCAAAGAAGTTCACGAATGGTTGGAAACATGTGGCTCTGTCGAAGACTTC
CCATTATTTGAAGCCGTATACCAAATCGTTTACAACAACTACCCAATGAAGAACCTGCCG
GACATGATTGAAGAATTAGATCTACATGAAGATTAG
Promoter Sequence
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>GPD1 YDL022W
AGCCCGAAAGAGTTATCGTTACTCCGATTATTTTGTACAGCTGATGGGACCTTGCCGTCT
TCATTTTTTTTTTTTTTCACCTATAGAGCCGGGCAGAGCTGCCCGGCTTAACTAAGGGCC
GGAAAAAAAACGGAAAAAAGAAAGCCAAGCGTGTAGACGTAGTATAACAGTATATCTGAC
ACGCACGTGATGACCACGTAATCGCATCGCCCCTCACCTCTCACCTCTCACCGCTGACTC
AGCTTCACTAAAAAGGAAAATATATACTCTTTCCCAGGCAAGGTGACAGCGGTCCCCGTC
TCCTCCACAAAGGCCTCTCCTGGGGTTTGAGCAAGTCTAAGTTTACGTAGCATAAAAATT
CTCGGATTGCGTCAAATAATAAAAAAAGTAACCCCACTTCTACTTCTACATCGGAAAAAC
ATTCCATTCACATATCGTCTTTGGCCTATCTTGTTTTGTCCTCGGTAGATCAGGTCAGTA
CAAACGCAACACGAAAGAACAAAAAAAGAAGAAAACAGAAGGCCAAGACAGGGTCAATGA
GACTGTTGTCCTCCTACTGTCCCTATGTCTCTGGCCGATCACGCGCCATTGTCCCTCAGA
AACAAATCAAACACCCACACCCCGGGCACCCAAAGTCCCCACCCACACCACCAATACGTA
AACGGGGCGCCCCCTGCAGGCCCTCCTGCGCGCGGCCTCCCGCCTTGCTTCTCTCCCCTT
CCTTTTCTTTTTCCAGTTTTCCCTATTTTGTCCCTTTTTCCGCACAACAAGTATCAGAAT
GGGTTCATCAAATCTATCCAACCTAATTCGCACGTAGACTGGCTTGGTATTGGCAGTTTC
GTAGTTATATATATACTACCATGAGTGAAACTGTTACGTTACCTTAAATTCTTTCTCCCT
TTAATTTTCTTTTATCTTACTCTCCTACATAAGACATCAAGAAACAATTGTATATTGTAC
ACCCCCCCCCTCCACAAACACAAATATTGATAATATAAAG
Chr coordinates
Chr IV from 411825-413000