Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NPC2 Systematic Name
YDL046W Strain
S288c Description
Sterol transport protein and functional homolog of human NPC2/He1; acts with Ncr1p in sterol trafficking; human NPC2 is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes; yeast NPC2 can complement mutations in human NPC2 External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NPC2 YDL046W
ATGACCCACAGCTTGAAAGCTCTATTCGCCTTGCTATTTCTTTACACAGCTGCTGTCAAT
GCGGGTGTGATTGGCATATTCAACGCCCTTCCCCCACCAAACACCAAACCAATTAACGGC
GAATCTCCACTTTACCAATGTGACATTCTAGACAAGCAACTTGTGGAAATCAAAGAGGTC
AATTTGGACCCTAACCCTCCTGTTCGTGGCGAAAATTTGACTATTTCTGCTAACGGTGAG
GTCTTTGAAACTATAGAAGAGGGGGCATATATCGACGTTGAAGTCCGTCTAGGATACATC
AGACTGTTATCCCAGACTTTTGATTTGTGTGAAACATTAGAAGATAACGATATCGAAGGC
TTATCCTGTCCAATTGAACCGGGTGAATACAACATTAAGAAAATAGTTGAGATCCCAGGC
GAGGTTCCACCTGGCAAATATGTTGTTGTAGCAAGAGCTTACACTGAAAAGGATGATCTG
ATCACTTGCTTAACCGGAGAAGTCATCTTCCCACCAAGGTGA Promoter Sequence
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>NPC2 YDL046W
ACGGTAAGATCTTATGTGTCCATGGAGGGTTATCTCCCGAGATTAGAATGCTCGATCAAA
TCAGAGTCTTGTCAAGAGCTCAAGAAGTGCCACACGAGGGTGGGTTCTCGGACCTGCTTT
GGTCAGACCCTGACAATGTAGAGGCTTGGCAAGTTTCCCCTCGTGGTGCAGGATGGCTCT
TTGGCAGTAAAGTTGCTAGAGAGTTTAACCACGTTAATGGACTGAACCTTATTGCCCGGG
CTCACCAACTGGTTATGGAGGGGTTCAAGTACCATTTTCCTGAAAAGGACGTTGTAACCG
TGTGGTCCGCGCCAAATTACTGTTATAGATGTGGTAATGTCGCGAGTGTAATGAAGGTCG
ATGAGGATCTGGAACCTACTTTCAAAATTTTCTCGGCTGTTCCCGATGACTACATAAGAG
AATCCACGGCAAACCATAATAATCAAAGAGCCGGCTATTTCTTATAACACGACGGCATGC
CCTCCCTAACTCGACGAATAAAAATAATTTTCACAATAAAAAAAAGACTACAAAAATCAG
AAACTTTTTCATTACGCCATTTGCTACGATACGATACACAACAAGCACATTCTAAGAGCA
TTCCATTTACTATGGTCAAAATGACCAAATAAAAAATTAAAAAAAAAAAGAAGGAATGAG
AACTAGTAACTACATATTCAACAATTGCAGTTTTCTTTTCCTTTTTGTCCTTGTCCTTTC
TTTCCTATTTATATATATATATATATATATATATAATACTACTATGTTATATTACATTAT
ATTATTATCACAATAATTATTACGTTCATCGTGCCGAAACGTCACCTCCCACGGTTTGGA
TCTATTGAAAGAGGGTGGAATCCCTGATAATAAAAAAACTTTAATCAACACTCGGGAGGG
GAAATATAAAAGACTGGCGCTACTTAAAGAGCTGATTCGCCAAGGCAGAAAAGCATAACC
ATATTAAATCTTCTCCTTCAAAGCTAGCACGCCTTCCAAA
Chr coordinates
Chr IV from 371240-371761
