Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SIT4
Systematic Name
YDL047W
Alias
PPH1
Strain
S288c
Description
Ceramide-activated, type 2A-related serine-threonine phosphatase; functions in G1/S transition of mitotic cycle; controls lifespan, mitochondrial function, cell cycle progression by regulating HXK2 phosphorylation; regulator of COPII coat dephosphorylation; required for ER to Golgi traffic; interacts with Hrr25p kinase; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization; similar to human PP6
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SIT4 YDL047W
ATGGTATCTAGAGGCCCCGACGAATGGCTTGAAACAATAAAGAAATGCCAGGCGCTAACT
GAAAACGAGATGAAACAACTGTGTGAAATGGTGAAAGAACTTTTGATGGAGGAAAGTAAC
ATCCAGCCGGTACAGACCCCCGTTACTGTATGTGGAGACATACACGGCCAATTTCATGAC
TTGTTAGAGCTATTCCGTACGGCGGGTGGCTTTCCTGACGATATAAACTACATTTTTCTC
GGTGATTACGTGGATCGTGGCTACTATAGTCTGGAAACTTTTACGCTTTTAATGTGTCTG
AAAGTCAAGTACCCGGCAAAGATAACTTTGGTCAGAGGAAACCATGAGTCCAGACAAATT
ACTCAAGTTTACGGGTTCTACGAGGAATGCCTGAATAAGTACGGATCTACCACCGTATGG
AAGTATTGCTGTCAAGTTTTTGATTTCCTGACGCTGGCCGCTATAATTGACGGTAAGATC
TTATGTGTCCATGGAGGGTTATCTCCCGAGATTAGAATGCTCGATCAAATCAGAGTCTTG
TCAAGAGCTCAAGAAGTGCCACACGAGGGTGGGTTCTCGGACCTGCTTTGGTCAGACCCT
GACAATGTAGAGGCTTGGCAAGTTTCCCCTCGTGGTGCAGGATGGCTCTTTGGCAGTAAA
GTTGCTAGAGAGTTTAACCACGTTAATGGACTGAACCTTATTGCCCGGGCTCACCAACTG
GTTATGGAGGGGTTCAAGTACCATTTTCCTGAAAAGGACGTTGTAACCGTGTGGTCCGCG
CCAAATTACTGTTATAGATGTGGTAATGTCGCGAGTGTAATGAAGGTCGATGAGGATCTG
GAACCTACTTTCAAAATTTTCTCGGCTGTTCCCGATGACTACATAAGAGAATCCACGGCA
AACCATAATAATCAAAGAGCCGGCTATTTCTTATAA
Promoter Sequence
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>SIT4 YDL047W
TGTTCTTTTTCTATTCAAAGACTCGAATGAGGCCAACGAAAGAAGTAGTAAAAAAAATCC
GGGATTCCCAATTCAGGTCATATCCGGCAAGACATTCCCGGATTTTATTTTCCTCAATGT
GCTCGTGTAAGTGTCGGCCCGGAACTTGATTCCCCCCGGACTAATTAGAAGTTCCGAGAA
CGCGCGCAAGCCGTCCCGCGCGTAGAAGGCTAAAAAGCAGCCGGAGGAAAAAAAATAACG
CAAATGTGGGCTCCCCTTCCCCTGTGCGGCCACGTCGTGCCTCCCCACCATTTGCCTCAT
ATGCGGCCATTGCGTGTGGTGTTTTTTCTGCTCTTGTCACTGATTTTAACTACCGCGGGG
TTTGACTAACAAGCAAATTGCAAAGCCGCGGCGGTTCCCGGAAAAAAAAAAAGGAAGGCC
ACGCTATTGGTAACCATGAAGTGTAAGGCGACGCAGGAGAGATGAAAAGAATGAAATTAA
AAGAAATCCAAAAAAAAAAAAAAAAAAAAAAAAGAAAAAGAAAGAAAAAGGGGGAATAAC
ACAGCCGCGGGTAACATGAAGCGGCGCGAGCGATACTTCCGTGTTAAGTGATATCCATCT
TTCTGCGGGTAATAAGTCTAGTCAAGTCCGCTGTATTTTTTCTTTCGCTCTCGCTCTCTT
TCTCTCTTCGCTCATGGAGCGGTAAAAAAAAAACATGCATATCGAGTCGAAGCCCAGCAA
AATTAAAAAAAATATAGCCTTCAGTGGAAACCCAGTGATGCTCGCACACAACGTAATGGA
GCATTGAAGAGCTACAGACGGTAGATAAAAAAGAAAAAGAAGCAATACAATAGGTTATTG
CATACTATCATAAGCATACAGATAAAGGAGTTCTGCACATACGGTCCCTCTTTCTCTTCC
TATTATTCTTCAGTCCCCTCCTCGCTCTTTTTAGATTCGACATTACAAGGTGAAATACTA
TTGAAGCTCAAAAACATCCATAATAAAAGGAACAATAACA
Chr coordinates
Chr IV from 369771-370706