Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
VAM6
Systematic Name
YDL077C
Alias
CVT4, VPL18, VPL22, VPS39
Strain
S288c
Description
Guanine nucleotide exchange factor for the GTPase Gtr1p; subunit of the HOPS endocytic tethering complex; vacuole membrane protein; functions as a Rab GTPase effector, interacting with both GTP- and GDP-bound conformations of Ypt7p; facilitates tethering and promotes membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking; component of vacuole-mitochondrion contacts (vCLAMPs) important for lipid transfer between organelles
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>VAM6 YDL077C
ATGTTAAGAGCTCAAAAGCTACACTCGCTGAAATCATCGGATATCACTGCGATTTTGCCC
ACTGAACAGTCACAAAAATTAGTTTTAGCAAAGAAAAATGGTGACGTTGAAGTTTACTCT
CGAGATGGCAATACACTCAAATTATTTCAAGTATATCCTGATCTCTTACAAAACGCCAAA
AATGATCCTTTGCCTCCAGTGATTGAAAACTTTTATTTTGCCAACGAGCTTTCAACTATC
TTTGCACAATGTAAAGAAACCTTAATTTTATTGAGCACTACAAATTTACACGAATATGAT
CGAATAATTGACAGAAGAGGTATAAACCATTGCTGGCTCTTTGAAAGGTCACACAAAAAT
AAAGAAGAAAAGAATACTTACCTAATATATTCAACCATCAATACTGCCAAGATGAGAGTA
TTAATATGGGAGGGTAGGACTTACAAAAATATGATGGAAGCATCGTTATCGTATAGAAAG
GAAACCATTCGGTCCATATATCCTGGTGAAACAGGAATCACCTTAGCGACAGATTTAGGT
ATCTATCATTGGCCATATAATAAACCCTCTCTAATCAGAATAGAAAAAACAGTGAAAAAC
AAATTCCCAAAAGATATGATATCAGCATTAACCGAACTCAAAGAGCAGGCGGAGAAAGTC
ATTGAAAAGAAGCCCAAAAAGAATAGCCATTTTGATGCTCAATCCTTTTCTTCTATGGAT
AGAATGTCCAGGAAGTCGAGCATGTCAAGCTTATGGTATAGGACCATAAGAAACGAGCGT
GGCAACAAAATACGATATACTTTTGAATTGGACGGCAATGACGCTACCCCAATGATAATT
GATGGTGCTACAAAAAAAATTTTCAAGGTAGAGTTAATGCATAACAATGAGGAACCATTT
TTGATCGCCACTGACCATGCTACATTTTCCGAATCAAATTCCGAATTCGATCACATGCAA
TATTTGTCGTCCAACCTCCTGATGTTATATAATTCAAGTACCATCAAGTTTGTTGATTAT
GAAAATGGATTTACTTTTTTGCAACAAAAAATACCAGAAGGTATAAAATGGGTCAAAAAT
CTCTCGGGAACCTACTTTTTAGTATGGACTTCAAACGACGAAGTACAGTTATTCTCTTAT
CATGTAGATGATGGCTCTGAAGATGATGATCAAGAGTCTATTTGTGGTGACATTAATGAT
CCTGATTTTTATCAACTATGGAGAAAAGTGCTTTTCTATAAGTTCTTCATTGATTCTCCT
CATTCTAAGGAGTTATGTGTTTCGGACAATCCAGAAGAATCCTTGGATATATGTGCTATG
AAACTAAGGGATTTAACAGTGATGTGGTGTCTAAGAATCTTCGATAAGTTTCAAAATTAT
ATGGTACAACTAGAAAGGAGTAGAAACTCGAGAATGATTCGTTCTAAATGTGAAGAAATG
ATCATCAAGAGTATTTTTGACCTATTTATAAAATTTTGGGCTCCACCTCAATTAGTTATT
TTGAAAGTTTTTCCCTCAGCCATTTCAAGCTTGGTATTGGAAATTACGGGCCAAGAGCAT
CACTGCTTGTTGAAGGAAGCCGAGGAGGTTAAGGAAACTTATGACATCCCGCCACACTTA
TTGAACAGATGGTGTTTACCTTATTTGACTGACACAAGGCGACATTTGCAAAACTTATTA
AGCAAGGAAAACGATGACGAAAGCCGCATAACTTGGTGCTATCGCGACCGTGAAATCAAG
CAAAGTTTTGATTTCTTTCTGATCAGCAACCACGATGATGTTGACCTTAACACAATGTTA
ACTCTGATAGATACAGTTTTATTCAAATGTTATCTTTACTATAACCCCCCCATGGTGGGT
CCATTCATTCGTGTAGAAAACCACTGCGATTCCCATGTTATAGTGACCGAATTAAAAATA
CGCCATATGTTCAAAGATTTAATTGATTTTTACTATAAACGTGGTAATCATGAAGAAGCT
TTGAAATTTCTCACGGATTTGGTCGATGAGTTGGAAAATGATAATACTGACCAGAAACAA
CGCCAAAAAATCGATCACGGTGTCAAAATATTAGTTATTTATTATTTGAAAAAATTATCA
AACCCGCAGTTAGACGTTATATTCACTTATACTGATTGGCTACTAAATCGACACAACGAC
TCAATTAAAGAAATCCTTTCCTCGATTTTTTTTTATGATTCTCAAGCCTGTAGCAGTAGG
GACCATTTGAAAGTGTATGGGTACATCAAAAAGTTCGACAAGTTACTTGCCATACAATAC
TTAGAATTTGCAATTAGTACTTTTAGATTAGAGGGAAATAAATTGCATACTGTCCTGATC
AAGTTATATCTTGAAAACTTAGATATTCCCTCCACAAGAATCAAATTAAAGTCTTTATTA
GAAACAACATCTGTCTATGAGCCTAGAACAATTTTAAAGTTATTGAACGATGCTATTGAG
AGTGGCTCTGACCAGTTGCCAACCAATCAACTAAATTTCGTAAAGTACCTAAAGATTTTC
CCCTTATCAAAATTAGAAAACCATAAGGAAGCTGTGCATATATTACTTGATGAGATAGAT
GATTACAAAGCGGCGACAAGTTACTGTAACGACGTGTACCAAAGTGATTCGACAAAGGGA
GAAGAGCTTCTATTGTACTTGTACAGCAAGTTAGTCTCCATATACGATTCCAATAGGAAC
TCCAAGCTGATTCTGAATTTTTTGCAAGACCATGGTTCAAAATTGAATTCAGCGGAAATA
TACAAAAATTTACCTCAAGATATTTCCTTGTACGATATTGGTAGGGTGGTGTCGCAATTA
TTAAAGAAGCACACATCAAAGATGGATGAGACCAGATTAGAAAAGGCACTCCTCCAGGTT
GAGCTTGTGGCCACCACATACAAACTCAATGAACGCATGTCATCGTATGGAGTCTTATCA
GATAGCCATAAATGTCCTATTTGCAAGAAAGTAATTTCAAATTTTGGAACAGATTCGATT
TCCTGGTTCACCAGGGAAGGCAGAAATATCATCACCCATTATAACTGTGGGAAAGTACTA
CAGGAGCGGTTTAACGCTAAAAATGAAAAGTCCTCGAGAATTAAACAGAAGACTTTGGGA
GAAGTTATAAATGAGCTAAATAATAAGTAA
Promoter Sequence
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>VAM6 YDL077C
TATGAAGATATTCAGGCAAGTTTCAATAATATAGAATCTCCTAGAAAGAGAAATAATGAG
ATATGGGGATGTGATATCTATTCTGATGACTCAGACCCAATACTAGTTTTAAGACATTGC
GGGTTCAAAATTGGAGCGCCTTCTGGTGGCTCATTTCACAAATTGAGAAGAACCCCTGTA
AATGTAACTAATCAAGATAATGTTACAGGTAACCTTCCCCTACTGGAAGGCACACCTTTT
GATCTAGAGGTGGAGTTGTTGTTTTTGCCTACTCTACAAAAGTATCCTAGCGTAAAAAGA
TTTGATATAACATCGCGGGAATGGGGATCGGAAGCCACCGTTATACACGATGGACTGAGT
TACGGTATCTATAGTATTGTCATTAAGCAAAGACTAGATAGAGATAAACCTCATGAACCA
AACGGGTATATTAAAAATTTAAAATGGACCTAAGGAAAGACATAATATTGGTCGTCCTTC
TTTCCCTTCCAACCTTAGTTGGCGCCATGTGTGTATTTAATTTAATTCAAAATATCATTC
TGCTGCGCTACTTCTGTATTATTGCTTTGAGGAATATACGATGCGTTGTACTATATAACA
AAAGCTTCACTTTATAAGTTTCTATAACTGGATAGTTTGGTTGTCTCACTCTCCTGCAAA
TTCATACTCTTCTTCCATACATTAACATGCCGTCCTAGGTGCTTGCTTTTTTAATTAGAC
TGGTTATAATATGTGTAACTAAGCCATTTTCGGGGCCCTCAGATTATATTAATTCCGAAT
CGGTAGTAAACGATATTTTATGAAAAGGACCCCAGGGCGCCAAACAAAACGTGGACTGTG
ACAAACTCTGCCAAAAGTCAAGCTCTAATCGTGTAAATCTTACCAATTGAGAGCGATTCC
TGTAATTAGGTTTACGGCTGTTCAATTATCTTTTCAACCGGACGGGTCTTATATTGATCA
GCAAAAACCCTTCAAAATATCAATTTATACCAAAAATTAA
Chr coordinates
Chr IV from 320120-316971