Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name GET3
Systematic Name YDL100C
Alias ARR4
Strain S288c
Description Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of GET complex, involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into ER membrane under non-stress conditions; binds as dimer to transmembrane domain (TMD) cargo, shielding TMDs from aqueous solvent; protein abundance increases under DNA replication stress
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>GET3 YDL100C
ATGGATTTAACCGTGGAACCTAATTTGCACTCTTTAATTACCTCTACCACTCATAAGTGG
ATTTTCGTTGGTGGTAAAGGTGGTGTTGGTAAGACTACTTCATCATGTTCCATTGCTATC
CAAATGGCTTTGAGTCAACCAAACAAACAGTTCCTACTGATCTCTACTGATCCTGCCCAT
AACTTAAGTGATGCATTCGGTGAGAAATTTGGTAAAGACGCCAGAAAGGTGACAGGCATG
AATAATCTATCATGTATGGAAATCGATCCATCCGCTGCTTTGAAGGATATGAACGACATG
GCAGTTTCACGCGCTAACAATAACGGAAGTGACGGTCAAGGTGACGATCTAGGAAGCTTG
CTTCAAGGTGGTGCTCTTGCTGATTTGACCGGTTCCATCCCTGGTATCGACGAAGCTTTA
TCCTTCATGGAAGTCATGAAGCACATTAAAAGGCAAGAACAGGGCGAAGGTGAAACCTTC
GATACTGTTATTTTTGACACTGCTCCAACTGGCCACACATTAAGATTTCTACAACTACCA
AATACTTTATCCAAGCTTTTGGAAAAGTTCGGTGAAATTACCAACAAATTGGGCCCAATG
CTAAACTCTTTTATGGGCGCAGGTAATGTCGATATCTCTGGAAAATTGAACGAGTTAAAG
GCTAATGTCGAGACCATCAGACAACAATTCACGGATCCTGACCTAACGACTTTTGTTTGC
GTTTGTATCAGTGAATTCTTATCCTTATATGAAACTGAAAGACTAATTCAGGAATTGATT
TCCTACGATATGGACGTTAATTCCATCATTGTCAACCAATTATTATTTGCTGAAAACGAT
CAAGAGCACAACTGTAAGAGATGTCAGGCAAGATGGAAGATGCAAAAGAAGTACTTGGAC
CAAATCGACGAATTGTACGAAGATTTCCATGTCGTTAAAATGCCATTATGTGCTGGAGAA
ATCAGAGGCTTAAATAACTTAACAAAGTTCTCACAGTTCCTAAACAAAGAATATAACCCT
ATTACTGATGGCAAAGTCATTTATGAGTTAGAAGATAAGGAATAG
Promoter Sequence
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>GET3 YDL100C
CTTGCGGTTTGCAAATCGTTTTGTAAACCATTAATGATGTCTTCTTTTTCCTGCAATTGA
TCCTGTAGGTCATCGACAGTAGTTTCATTTTCCATATTCAAAAATTTCAGTTGTTTATTT
TCCTGTGTGAGTTTCTCATTTTCCGCCCTTAGTTTGGTCAACTCATCTTCTTCTTTTTGC
TTTTTAATCGTGGTGAGAAAGTCAGATTCTTCATTGCCGTCATTGGCAAATAAATCGTCT
GCTGCTTCTGATGTATTTGAAGGTTCGTTTCCTTCTTGAGTTTGTACAATTTTCTTTTCC
TCTTGTGGTTCTATGGTCTTTCCGGCATCTGCTGTTTGCTCATCGTTGTTATTTTTTATA
ACTTCTTGAACTTCCTCTTTTTTTGTGTTTTCTGCATCATCCTTTCCCACATTTGATGAA
GTACTATTTATTTCCTCAATATCTTTTTCTGTTGTGCCCGAAGGATCTGATTTAACCTGT
TCTATTTCTTTTTCTTCACTCTCCTCATCCACGTCATTTTGATCGTTGTTTTCACTTTTG
GTGGAATTTGCTTTCACAGTCTCCTCCTGTGTGGACTCTTCGCCTGGTGTGCCCTCTAAA
TCAGGAGTTTCAGATCCTATAGAGCCTGTGGCACTGCTATTTTTATTCTTCTTACCTTTA
TTCTTTTTATTTTTCTTTTTCTTCAATTCTTCTACTCTCTTTCTAGCCTCTTCCAATTGT
TTCATACGCTTAACTTCATCAGACTCCTGTTCAGACATTGTAACTATATGATAAACTTGC
TCAATTCAGGTTGGTTCAATGCAAATTATTACATCCCTTTTTTATCACAAGATCTTCGTA
ACAATAGTACTAATTAATAGTGCTGGGGATTCTCAACCATTTTTTTTTTTTCAAAAGCGA
AAATGGATAAAACGGTGGCAACTTCAAACAAGTTGAGGGAAGCCAACGCAGCGTTTAGGA
AAACGTACGACAAGAACAAGAAGATCATCACATTGTAATT
Chr coordinates Chr IV from 283176-282112
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