Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name KIN28
Systematic Name YDL108W
Strain S288c
Description Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly; phosphorylates the C-terminal domain (CTD) of RNAPII (Ser5 and Ser7); facilitates recruitment of mRNA 5'-capping and polyadenylation factors to the RNAPII holoenzyme complex; minor role in RNAPII transcription; role in RNAPI transcription; regulates Atg1p kinase complex assembly during nitrogen starvation induced autophagy; associates with cyclin Ccl1p; relocalizes to the cytosol in response to hypoxia; ortholog of human CDK7
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>KIN28 YDL108W
ATGAAAGTGAATATGGAGTACACAAAGGAAAAGAAAGTTGGTGAGGGTACTTATGCGGTT
GTTTACTTGGGTTGTCAACACTCTACTGGAAGAAAGATTGCTATTAAGGAGATCAAAACA
TCCGAATTTAAAGATGGTTTAGATATGTCAGCTATCCGTGAAGTTAAGTACCTCCAAGAA
ATGCAGCATCCGAACGTCATAGAACTAATAGACATATTTATGGCTTATGATAATTTAAAT
CTCGTTCTGGAGTTCCTACCAACTGATCTAGAGGTGGTAATAAAAGACAAATCAATACTG
TTTACACCAGCAGATATTAAGGCATGGATGCTTATGACTTTGAGGGGCGTGTATCATTGC
CACAGAAATTTCATTTTGCACAGGGATCTGAAACCAAACAATTTATTATTTTCACCTGAT
GGCCAGATAAAAGTAGCAGATTTCGGTCTAGCAAGGGCGATACCGGCCCCACATGAGATA
CTGACAAGTAACGTCGTAACAAGATGGTATAGAGCGCCAGAATTGTTGTTTGGAGCTAAA
CATTACACATCGGCTATTGATATCTGGTCAGTAGGCGTTATATTCGCGGAATTAATGCTA
AGGATACCTTATTTACCAGGACAGAATGATGTCGATCAAATGGAAGTAACGTTCAGGGCC
TTAGGGACACCTACAGATAGAGATTGGCCCGAAGTTTCTTCCTTTATGACGTATAACAAG
TTACAAATATATCCGCCCCCTTCAAGAGATGAATTGAGGAAAAGGTTCATTGCTGCTAGC
GAATACGCCTTAGATTTTATGTGTGGAATGCTAACGATGAACCCACAAAAGAGGTGGACC
GCTGTTCAGTGTTTAGAAAGTGATTATTTCAAAGAATTACCACCACCAAGTGACCCGTCT
TCAATAAAAATACGTAACTGA
Promoter Sequence
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>KIN28 YDL108W
TGTGTGTAAAATATTGCAGGCTTTATCAGGCAATGAATCATTACATCGTATTTTTCTTTT
CAAAGAGGCCTTTGAATTGCCGACTACTATCTCAAAAGTTACCTTAGTTTCTTTATTAAA
TAGTATTTGACTGACAATATCCACTATCCATACATAGCGTGGCTTAATGTGGTGCAAGGA
CAACTCTGCAATAAACTTTTGTTGTGCCTGTAGGTTTGATTGAAATACTGGTTTATCCGC
CGAACATATGATCTTATACGAGCTTTCGTAATCTTTTGCTCGCACGTCACAATATAAGAT
AAATGGGCCCAATAGATAGGCTGGTTTATAGGATAGCTTTGTGGTATTTTTGATCTTTAC
CCATAGGGAATCCAGTGTGATATCAGCGGGAATACTATCACCCTGGTATAGCTCATATGT
AATAACGTATCTTTCTAACTCACCTAACTTTACTGACGACTGATTGTGGTATAGCACTTC
ATCAGCACTCCTGCCAGCTTCCATATTACTACCGTTTCCCCGATGTTTTTGGGTGAATAA
GGTCAGGTGAGCATTTTTTGTACTGATATTTTTTCTCTTTGTTTGCAGACACAACGCTTG
CTGTTAATACGCTAAAAACATACCACACTACCTTGAACAAATCCTCCAAGAGAAATTTGT
AAGAATTCAGAAGCGGTTTCAGGGGAAGTCGGCTTAGTTGTCAATTGTAATTGAAAATCA
CCCTCTAATTTGAAAGATTTTCAGTTTCAATAAGACATCAATCTTGCCAGTTTGTAATTT
TTTGGTATATAGAAATGGTCTTCAAGCATAAGCCTTAAGAAAGATTCGTCCATTGGATGA
ACCTACAATTTTTTTTGTGTTATGATGTGAAGCTTCATTTGAAGCATTGTGCAGAGAATA
TTACAAGTAGATTCAAAAAACACATTGAAAAAAAATACAAGTGAAATCACAGTTACTTAA
AAGTCATCAAAAAAAATATTCCCGGCCTCAGAGCGAACAT
Chr coordinates Chr IV from 267698-267725,267807-268699
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