Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IWR1
Systematic Name
YDL115C
Strain
S288c
Description
RNA polymerase II transport factor, conserved from yeast to humans; also has a role in transporting RNA polymerase III into the nucleus; interacts with most of the RNAP II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to K1 killer toxin; protein increases in abundance and relocalizes from nucleus to cytoplasm upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>IWR1 YDL115C
ATGAGCACTATTAGTACCACAACGGCACCTGAGTTTATCAGAGTAAAGAGAAGAAGGGAT
GAGGATTCTGTGCAGGCATTATTAATTGATGAGGGGAAAAGAGTGAAGAAGCAGAAGTTC
ATATTTAAATTATCAAAGACTGTGAGCTCTGAAAGCTATCAATCCGAGCAAGAGTCTTCT
ACGCCACTCTTAAAACTGGCTCATGAAGATCATCGACATTTTGTATTGGAACAAAGAAAA
AAAAGTCGTAGAGACTCAGATGATGAAAAATCACAACAGCGGCTTGCAGCAGAAGGAAGT
ACTGTAGATGACGATGGGTTACCGCCAGAGATCAATCAAATGGTGAATGACTATTTAAAG
TTGAATAAAGGTGTAGAAAAGACAGAAAGAAAAAAACCAAGTAGGAAATATTTTACTGGG
GATTCTGCAAAAATTGCATCACTACCCAGTTTAGATTACGTTTTTGACATCTACCATTTG
GAGAAAATTCATGACGATGAGGTTGCTAGATATAACAACGAGAAAAATATAGGGTTTGTG
AAAATTATTGAGCATATAGATTTGGCTCTTGATGAAGAAAGTGATCCCAATGAAGCCCGT
TCAGACGATGAGGATTCTAATGACGAAAACTATTACCAAAATGATTATCCGGAGGATGAA
GATGATGATAGATCTATTCTATTTGGTAGCGAAGGAGAGGATATAGCTGCATTGGGTGAA
GAGATTGTTATAGGGGTTAATAAGAGCAGGTTTTCCTCTTGGAATGACGATAAAATTCAG
GGATCTAATGGGTACCACGATGTGGAGGAAGAGTACGGGGATCTTTTTAACAGGCTTGGA
GGAAAAAGTGATGTCTTGAAATCCATAAATTCCTCGAATTTCATTGACTTGGATGGCCAA
GAAGGTGAAATAGAGATAAGTGATAACGAAGATGATTCTGATGAAGGAGATGATATTGAA
TACCCTAGAAATGAATTTTTTCCGACGGATGTTGATGACCCATTGGCGCATCATAGGGAC
AGAATTTTTCATCAGCTACAGAAAAAAATTAATAGAAGCTAA
Promoter Sequence
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>IWR1 YDL115C
TCAGTTCTCCGAGGACTGAAGCAATGTTAATTATAAAGCCTTCCCTATTGTCTATCATAT
CTTCTGCAAATGTACTGATGATTCGGTAAGCACCTATTAAGTTTATGTCGATCAATTGTT
CTACCTCCTTGTTTGTCATATGTTCTAACTTTTTGATGTGAGCAACACCAGCATTATTTA
TAATTATATTAATGTTGCCATGATCTCTTTCAATAGCTTTTTTCAAATTTTTAATTTCAT
CTAGACTTGTTATGTCGCATTGATAGTAGAAAATGTTATTATATTCTACCTGAGCAAAAG
TAGGAAATGATTGAATATCTGCCACAATAACTTTATTAATTCTTCTGGAAAGTTCCTTTG
CAAGTTCAAATCCGAGTCCACTAGAACCACCGGTTATTAGTGCAGTTGCATTTTTAGAAA
GGATGGAAGGGTTGTAGCTGGGCAGACTTAGGATGACTGATGGAAAATCCTTGAGGTGTT
TTGTAGTTCCACTCGCTCTATTTATTTTATTCTTGCGTACCATAATTAATAATATTTCTT
ACCCATAAAACTATGTTAAATATGTCACTGAATCTCTATTGAGGTGTCCTTTTGATGATG
CGGTTTCAGATATGAGAAATGTTCATTCAAGAAGTGTCACAAATTCTGTTCCTCTGCTGA
CGCCCGCTACATATTGACGTTCAAAAATATAGAAGAAAAAGGCAGTAAAGCGTTAACATA
AGAAAACTAAAGAGCAAGTCTGATTTGGCACTACCACGCTTCCAACAGAAGTAATTGTTG
CTTCAAATAAGTTCGCAGCATGTGGATTCAAGTCCACAGATGCGATATTTAGGAGCCCAA
TCAGATAATATTGATTCCGGGTTATCTCTTGTTTGTGTCGGCACAGGGGATTTAAATTGT
GTAATGCTCAAGACAAGTTATTGATGAGAACAAGAGATGGTATATAAAACTGCTCTCTGA
GGTATAGCTTTTGTTGAGGTAGGCATACAAGATTTCGGGA
Chr coordinates
Chr IV from 254974-253995,255126-255045