Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
LYS21
Systematic Name
YDL131W
Strain
S288c
Description
Homocitrate synthase isozyme; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS21 has a paralog, LYS20, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>LYS21 YDL131W
ATGTCTGAAAATAACGAATTCCAGAGTGTCACCGAATCGACGACTGCTCCAACCACTAGT
AACCCATATGGCCCAAATCCTGCGGATTATCTATCCAATGTTAAGAATTTCCAGTTGATT
GATTCAACACTAAGAGAGGGTGAACAATTTGCCAACGCATTCTTCGATACTGAAAAAAAG
ATTGAAATTGCTAGAGCCTTGGATGATTTCGGTGTGGACTACATCGAGTTAACCTCTCCC
GTAGCATCCGAACAATCAAGAAAGGACTGTGAAGCTATATGTAAACTAGGTTTAAAGGCC
AAGATCCTTACACACATTCGTTGTCACATGGACGATGCCAGAGTCGCCGTAGAGACTGGT
GTCGACGGTGTCGATGTTGTTATCGGCACCTCCAAATTTTTAAGACAATATTCCCACGGT
AAGGATATGAACTACATCGCCAAGAGTGCTGTTGAAGTCATTGAATTTGTCAAATCCAAA
GGTATTGAAATCAGATTTTCCTCTGAAGATTCCTTCAGAAGTGATCTCGTTGATCTTTTG
AACATTTATAAAACCGTTGACAAGATCGGTGTAAATAGAGTCGGTATTGCCGACACAGTT
GGATGTGCCAACCCAAGACAAGTATATGAACTGATCAGAACTTTGAAGAGTGTTGTCTCA
TGTGACATCGAATGCCATTTCCACAATGATACCGGTTGTGCCATTGCAAACGCCTACACT
GCTTTGGAAGGTGGTGCCAGATTGATTGACGTCAGTGTACTGGGTATTGGTGAAAGAAAC
GGTATCACTCCTCTAGGTGGGCTCATGGCAAGAATGATTGTTGCCGCACCAGACTATGTC
AGATCTAAATACAAGCTGCACAAGATCAGAGACATCGAAAACCTGGTCGCTGATGCTGTG
GAAGTTAACATTCCATTCAACAACCCTATCACCGGGTTCTGTGCATTCACACATAAAGCA
GGTATCCATGCCAAGGCCATTTTGGCTAACCCATCTACCTACGAAATCTTGGACCCTCAC
GATTTCGGTATGAAGAGATATATCCACTTCGCCAACAGACTAACTGGTTGGAATGCAATC
AAATCAAGAGTCGACCAATTGAACTTGAATTTGACGGATGATCAAATCAAGGAAGTTACT
GCTAAGATTAAGAAGCTGGGTGATGTCAGACCGCTAAATATTGATGATGTAGACTCCATT
ATCAAGGACTTCCATGCAGAATTGAGCACCCCACTTTTAAAACCAGTAAATAAGGGTACA
GATGACGACAATATCGATATTTCCAATGGGCATGTTTCTAAAAAGGCAAAGGTCACCAAA
TAG
Promoter Sequence
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>LYS21 YDL131W
CGCTTAAGACCAATATTAATTTCGCTAGCGGAGTCAAAAACGACATTCTGCAATCGCTAT
CCGGTGGAGGCCACGATAATCACGGTAATAAGTTAGGAAACAAACGCTTGACGGAAGACG
AAAGAATAGAAAAAGAATTGAATACAGAAAGGCAGATTTTCTTGGAAGCTTGTATTGTGA
GAATAATGAAAGCGAAAAGAAATCTGCCACATACAACATTGGTCAACGAATGCATTGCGC
AATCACACCAAAGGTTCAATGCAAAGGTTTCTATGGTCAAGAGAGCCATCGATAGCTTAA
TACAAAAGGGATACCTACAGAGGGGAGACGATGGTGAATCGTATGCTTACCTTGCTTAAT
CATCTTTGAAGGCTTGTGCTGATCGAACGAAGCAAATCCTACGAGTAAATACATAAGCGT
ATACATATATATATATATATATATATATATATATATATGTATATATATATATGTGTGTGT
GTGTAATTGTGTGTATTCAACTGAACTATGAAGAGTCTTTGACCTCTTGAGAATCTCATA
GTATGAAGATATGGCACTTCTCTTTCCGTTGTAACATCCTTTACCGGGCGGCTTTTCGGC
CTGCTTGAGAAGAGATCAGGCTGAAATGATGAGACTGACAACAAGGATCAGTCAGTGGCA
GAGTTGAAATTCCGCTGGAAATCGTCACCAGCAGCTACCAGCTCCAAGAAATCCGCGTAG
AAATCACGTCGCGCAATGTGCGATAGTGGTGGAACAGCGAAAATTAGTCACTTTGCAAAG
ATGCCAAGCTGATCGTTCTCGTTGTGTGTGATTCTACGATATTGCGCATGAGTGGTGTTG
AGCATGCGTTTGTTCGCATTTTCATGCAGTCTCTTATATACTAATATATATATGCAACAG
ATTTCAAAATTTATCTTTCTTCTTGTTGCGTTTAGGCCTTTATTTGCTACACATTTAAAA
GTGCAACGACAACCCAAGTAATTGTATACTTTAACAAACC
Chr coordinates
Chr IV from 227393-228715