Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CDC53
Systematic Name
YDL132W
Strain
S288c
Description
Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation; human homolog CUL1 can complement yeast cdc53 null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CDC53 YDL132W
ATGTCTGAGACTCTGCCTAGATCTGATGATTTAGAGGCCACTTGGAACTTTATAGAGCCA
GGAATTAACCAAATACTGGGTAATGAGAAAAACCAAGCATCCACGTCTAAGCGAGTTTAC
AAAATTCTTTCTCCAACCATGTATATGGAAGTCTATACCGCAATTTATAACTACTGTGTG
AACAAATCACGCTCGTCTGGACATTTTAGTACTGACAGTAGAACTGGCCAATCAACAATT
TTGGTTGGCAGTGAGATTTACGAAAAGTTAAAGAATTATTTGAAGAATTACATTTTAAAT
TTTAAGCAGTCTAATTCAGAGACCTTTTTGCAGTTTTACGTCAAGCGCTGGAAAAGGTTT
ACAATAGGTGCCATTTTTTTAAACCATGCATTCGATTATATGAATAGATATTGGGTTCAA
AAGGAAAGAAGTGACGGCAAAAGGCATATTTTTGATGTAAACACCTTGTGCTTGATGACA
TGGAAAGAAGTCATGTTTGATCCGAGTAAAGATGTTTTAATAAACGAATTATTAGACCAG
GTAACCTTGGGAAGGGAGGGGCAAATAATTCAAAGAAGTAATATTAGCACTGCCATAAAG
TCTTTAGTTGCACTAGGTATCGATCCACAGGATTTGAAAAAGTTGAACCTAAATGTCTAC
ATCCAAGTTTTCGAAAAGCCATTTTTAAAGAAGACTCAGGAGTACTACACGCAATATACA
AACGATTATTTAGAGAAACACTCGGTAACTGAGTATATTTTTGAAGCACATGAAATCATC
AAACGTGAGGAAAAAGCAATGACAATATATTGGGATGATCATACAAAAAAACCACTATCC
ATGGCATTAAACAAGGTCTTGATCACAGACCATATTGAAAAGTTGGAAAATGAGTTTGTT
GTCCTTCTGGATGCCAGAGATATTGAAAAAATTACTTCTTTGTACGCACTAATACGCAGA
GACTTTACATTAATCCCAAGAATGGCTTCAGTGTTTGAAAATTATGTTAAAAAGACAGGT
GAGAATGAAATTTCGAGTCTACTGGCAATGCATAAACACAATATTATGAAAAACGAAAAC
GCAAACCCTAAAAAACTAGCACTAATGACAGCTCACTCCCTTTCTCCTAAAGACTATATC
AAGAAATTACTGGAAGTACACGATATATTCTCTAAGATTTTTAATGAAAGTTTCCCCGAC
GACATACCTTTAGCTAAAGCTCTAGATAATGCGTGTGGTGCTTTCATCAACATCAACGAG
TTCGCATTACCTGCTGGATCTCCAAAAAGTGCCACCTCGAAGACTTCCGAGATGCTAGCT
AAGTACAGTGATATACTATTAAAGAAGGCCACCAAACCTGAAGTGGCAAGTGACATGTCA
GATGAAGATATTATAACAATATTCAAATATTTGACCGACAAAGATGCGTTCGAAACTCAT
TATAGAAGACTTTTCGCCAAGCGTTTAATTCATGGCACTTCAACATCAGCAGAAGACGAA
GAAAATATTATTCAAAGGCTGCAAGCGGCAAATAGTATGGAATATACAGGCAAGATAACT
AAAATGTTTCAAGATATTAGACTTTCCAAGATCTTGGAAGACGATTTTGCTGTCGCCCTG
AAGAATGAACCAGATTACTCTAAAGCAAAATATCCAGATCTACAACCATTTGTATTGGCA
GAAAATATGTGGCCATTTTCATACCAAGAAGTTGAATTTAAGCTACCCAAGGAATTGGTA
CCATCTCACGAAAAATTGAAGGAGTCATACAGCCAAAAGCATAATGGTAGAATATTGAAG
TGGCTATGGCCATTATGTCGTGGCGAATTGAAGGCAGATATTGGAAAACCCGGCAGGATG
CCGTTCAACTTTACGGTAACACTGTTTCAAATGGCAATTTTGCTACTATATAACGATGCT
GATGTATTAACCTTAGAAAATATTCAAGAGGGCACGAGCTTAACCATTCAGCACATCGCA
GCGGCAATGGTACCATTCATCAAATTCAAACTGATTCAACAGGTCCCACCAGGGCTAGAT
GCTCTCGTGAAACCTGAAACACAATTCAAGCTATCACGTCCTTATAAGGCGCTTAAGACC
AATATTAATTTCGCTAGCGGAGTCAAAAACGACATTCTGCAATCGCTATCCGGTGGAGGC
CACGATAATCACGGTAATAAGTTAGGAAACAAACGCTTGACGGAAGACGAAAGAATAGAA
AAAGAATTGAATACAGAAAGGCAGATTTTCTTGGAAGCTTGTATTGTGAGAATAATGAAA
GCGAAAAGAAATCTGCCACATACAACATTGGTCAACGAATGCATTGCGCAATCACACCAA
AGGTTCAATGCAAAGGTTTCTATGGTCAAGAGAGCCATCGATAGCTTAATACAAAAGGGA
TACCTACAGAGGGGAGACGATGGTGAATCGTATGCTTACCTTGCTTAA
Promoter Sequence
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>CDC53 YDL132W
ACTCAAGATCAAATAACACCATCAGTGAAAGTAAAATCGGGCAACAACCAAGCACCATAA
TGGCCATCTGCGTCAACGCCGTGGCGATTGCGTATATTATTTACATTGCACACGATGAAT
TTGCTGGTAAACCTGTTGGTTTGAGGAATCCGTTAAGCAAACTGAAACTAATTTTGTTGG
ACTTACTTTTTATAATTTTTTCAAGCGCTAATCTAGCGCTGGCATTTAATACTCGTTTCG
ACAAAGAGTGGGTTTGCACTTCTATTCGCAGGTCAAATGGAAGCACGTATGGATACCCAA
AAATACCGCGTATCTGCAGAAAACAGGAAGCTTTATCCGCTTTTCTGTTCGTTGCCTTGT
TTATGTGGGTAATCACTTTCTCGATCAGTATTGTTAGAGTAGTCGAAAAAGTCAGTTCAA
TTACCAACAGAAACTGAGCTCGACAAATATAGAAATTAAAAGAATTCTTTTAGATACCAA
GATTGACATTTATATGCATTGTATATTTTTGACTTAAAAAATTACTCCGGCTTGGCATTT
ATTCATTAACGGCGGGTTTGATTATATTAGGCTTTGTGCGATATAATATGTATTACCCGA
AGGGAGGGCTATTGCACTTTCTTTTCCTTTCCGTTTTAAGGGCCCTTTTTCATTTCGATG
TTTGATGGACACACATGAAGTGAAATGTGGCAAATAGAACATCTAGAAAAACTAGGGCAT
TAGGTAAAGTACCCCAGCAGAACTTCACTTTACAACGCAATTGATTCATATCACTGCTCT
TTTATATTGTCCTTTTTCTCTTTTAGAGCTTTTCATCCGCATCTTCTAACTTCTGTGCAC
CCCTTTCATTGTTGATTACATTTTACCTCAGTTACACATTTCTTTTAGCAATTCGACATT
GCTTCTACTTACCGATAAATAAGCGTACATTTTTGAGTCTTGAAAGGATTCTTACATATA
CCTAAACAAAGAATAACAACAAAATCGCAAGCAGCAAAGC
Chr coordinates
Chr IV from 224304-226751