Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PPH21
Systematic Name
YDL134C
Strain
S288c
Description
Catalytic subunit of protein phosphatase 2A, PP2A; functionally redundant with Pph22p; C-terminally methylated; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; forms nuclear foci upon DNA replication stress; PPH21 has a paralog, PPH22, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PPH21 YDL134C
ATGGATACAGATTTAGATGTGCCTATGCAAGATGCTGTTACCGAACAGCTGACTCCCACA
GTATCTGAAGATATGGATCTCAACAACAATTCATCGGATAATAATGCAGAAGAATTCTCG
GTTGATGATTTAAAACCTGGTTCCTCGGGCATAGCAGATCACAAATCTTCCAAACCACTA
GAACTGAATAACACAAATATAAATCAGCTTGACCAATGGATTGAGCATTTGAGTAAATGC
GAGCCACTATCAGAAGACGATGTAGCACGACTATGTAAAATGGCGGTGGACGTGTTGCAG
TTCGAGGAGAATGTTAAACCAATTAACGTGCCTGTTACCATTTGTGGTGACGTACACGGT
CAATTCCATGACTTGTTAGAACTTTTTAAGATTGGTGGCCCTTGTCCTGACACCAATTAC
CTTTTCATGGGTGATTACGTGGATAGAGGATATTATTCTGTTGAAACTGTATCTTACCTA
GTTGCCATGAAAGTCAGATACCCACATAGAATTACGATACTGAGAGGCAATCACGAGTCT
AGGCAGATTACCCAAGTATACGGGTTTTATGATGAATGTTTGAGAAAGTACGGCAGTGCA
AACGTGTGGAAAATGTTCACAGATCTTTTCGATTATTTTCCTATAACCGCATTAGTAGAT
AATAAAATTTTCTGTCTGCATGGAGGACTTTCCCCCATGATAGAAACCATAGATCAGGTG
AGAGAGTTGAACAGAATACAGGAAGTGCCTCATGAAGGTCCTATGTGTGACCTTCTATGG
TCAGACCCTGACGATAGAGGCGGATGGGGAATCAGTCCCAGAGGTGCAGGCTTCACTTTT
GGACAAGATGTCAGTGAGCAATTCAATCACACTAATGATCTATCACTAATAGCAAGAGCT
CACCAATTGGTAATGGAAGGCTATGCTTGGTCTCACCAGCAAAATGTTGTCACCATTTTC
AGTGCTCCTAATTACTGCTACAGATGTGGTAATCAAGCAGCTATCATGGAAGTGGACGAG
AATCATAATAGACAATTCTTACAGTACGACCCATCCGTAAGACCAGGTGAACCTAGCGTC
AGCAGAAAGACGCCAGATTACTTTTTATGA
Promoter Sequence
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>PPH21 YDL134C
AGAAGACTTAAGAGAAAGAGACGGAAGGTGAGAGCCAGATCCAAATAAGCGGATTGAGAG
CAAATCGTTAAGTTCAGGTCAAGTAAAAATTGATTTCGAAAACTAATTTCTCTTATACAA
TCCTTTGATTGGACCGTCATCCTTTCGAATATAAGATTTTGTTAAGAATATTTTAGACAG
AGATCTACTTTATATTTAATATCTAGATATTACATAATTTCCTCTCTAATAAAATATCAT
TAATAAAATAAAAATGAAGCGATTTGATTTTGTGTTGTCAACTTAGTTTGCCGCTATGCC
TCTTGGGTAATGCTATTATTGAATCGAAGGGCTTTATTATATTACCCTTTAGCTTATTCT
GAGGTTTCTGTGGCGTGCAAAGTGATGAACCGGGCGGGTTTTAAGGATAAAATCAAAAAG
TGAAAAAATGAACGGAAAATGGAATACCTGTGAAATGGAGAATGATAATGAATCTTTCTG
TCGTGCTTGAAAGATTTTCGGCTATTTTAATCGACTAACACATAGTAGTAGAAATAGTTT
TCCGGATTACATTAGTTCGGCATTCTTTTTAGCAGGTTTTTGTTACAGGTTCCTTTCGAC
GCACCGTTTCACAGTAAAGGAGGTAATTAGTGAATCAGACGCTGCACTTTCATTGATTTT
GATATACACATACTCCAATTAGTTTTAGTGTAAATTAAATTGCCCCAGTGGACACGATAT
TTACAAAAAGTGTTTTATTCTTCTTAGAAATACACCTGTTGGACTGCTCTTTTTTCACTC
GTCTTCCCCTAGTTTTCTTTCCTTACCAGTAATTTAGTAAGAGTTTAGTGAGTTCAGGTT
GAATAGAGTTATTATCTAATTTTAAACTGTTAATTTTACCGGTTGTGTTTTTTGAAATAA
GGCAAAAGAGAAAGAAAAAAACAAATTATTTTGCCCCTATTTAGTTCATAGTGGAAAGAG
GGATATAAATTATCGCATAAAACAATAAACAAAAAGAAAA
Chr coordinates
Chr IV from 220771-219662